Monday, September 21, 2009

Disruption to higher order processes in Friedreich ataxia

doi:10.1016/j.neuropsychologia.2009.09.009
Received 1 April 2009; revised 21 July 2009; accepted 11 September 2009. 

Available online 17 September 2009.

Joanne Fieldinga, b, c,, Louise Corbend, e, Phillip Cremerf, Lynette Millistc, Owen Whiteb, c and Martin Delatyckid, g
aCentre for Neuroscience, University of Melbourne, Parkville, Victoria, Australia
bCentre for Developmental Psychiatry and Psychology, School of Psychology, Psychiatry, and Psychological Medicine, Monash University, Clayton, Victoria, Australia
cDepartment of Neurology, Royal Melbourne Hospital, Parkville, Victoria, Australia
dBruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Victoria, Australia
eExperimental Neuropsychology Research Unit, School of Psychology, Psychiatry, and Psychological Medicine, Monash University, Clayton, Victoria, Australia
fRoyal North Shore Hospital, N.S.W., Australia
gDepartment of Paediatrics, University of Melbourne, Victoria, Australia

 Keywords: Friedreich ataxia (FRDA); cognition; saccades; cerebellum  

Mitochondria in neurodegenerative disorders: regulation of the redox state and death signaling leading to neuronal death and survival

Journal of Neural Transmission,

Makoto Naoi1 , Wakako Maruyama2, Hong Yi1, Keiko Inaba1, Yukihiro Akao1, 3 and Masayo Shamoto-Nagai2


(1) Department of Neurosciences, Gifu International Institute of Biotechnology, 1-1 Nakafudogaoka, Kakamigahara Gifu, 504-0838, Japan

(2) Department of Geriatric Medicine, National Institute for Geriatrics and Gerontology, Obu, Aichi, Japan

(3) United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan

Received: 4 March 2009 Accepted: 30 August 2009 Published online: 18 September 2009

Keywords:  Apoptosis - Mitochondria - Oxidative stress - Redox state - Neuroprotection - MAO inhibitor