Wednesday, August 11, 2010

Friedreich’s Ataxia Induced Pluripotent Stem Cells Recapitulate GAA•TTC Triplet-Repeat Instability

NCBI, Public on Jul 02, 2010

Experiment type: Expression profiling by array

Keywords: Friedreich’s ataxia (FRDA), GAA•TTC trinucleotide repeats, FXN gene, induced pluripotent stem cells (iPSCs), fibroblasts, retroviral transduction, Msh2, repeat instability.

A Phase 3, Double-blind, Placebo-Controlled Trial of Idebenone in Friedreich Ataxia

Arch Neurol. 2010;67(8):941-947. doi:10.1001/archneurol.2010.168

David R. Lynch, MD, PhD; Susan L. Perlman, MD; Thomas Meier, PhD