Wednesday, August 25, 2010

The Monash University are seeking healthy participants for the control group, Understanding Motor Deficits in Friedreich's Ataxia

The aim of this study is to investigate the extent of motor overflow in people with Friedreich's ataxia. Motor overflow refers to involuntary movement which occurs on the opposite side of the body when voluntary movement takes place on one side.

Defects in Mitochondrial Axonal Transport and Membrane Potential without Increased Reactive Oxygen Species Production in a Drosophila Model of Friedreich Ataxia

The Journal of Neuroscience, August 25, 2010, 30(34):11369-11378; doi:10.1523/JNEUROSCI.0529-10.2010

Yujiro Shidara {dagger} and Peter J. Hollenbeck
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907

KEYWORDS: Friedreich ataxia, frataxin deficiency, oxidative stress, cellular neuropathology, mitochondrial axonal transport, membrane potential (MMP), reactive oxygen species (ROS), neuromuscular junctions (NMJs), antimycin A.

Long-term effects of coordinative training in degenerative cerebellar disease†

Movement Disorders, Article first published online: 24 AUG 2010, DOI: 10.1002/mds.23222

Winfried Ilg PhD1, Doris Brötz PT2, 3. Susanne Burkard PT3, Martin A. Giese PhD1, Ludger Schöls MD4,*, Matthis Synofzik MD4.