Monday, January 9, 2012

Solving the Structure of a Protein That Shows Promise as a DNA-Targeting Molecule for Gene Correction, Therapy

ScienceDaily, 5 Jan. 2012. Web. 9 Jan. 2012.
Fred Hutchinson Cancer Research Center. "Solving the structure of a protein that shows promise as a DNA-targeting molecule for gene correction, therapy."

ScienceDaily (Jan. 5, 2012) — Researchers at Fred Hutchinson Cancer Research Center have solved the three-dimensional structure of a newly discovered type of gene-targeting protein that has shown to be useful as a DNA-targeting molecule for gene correction, gene therapy and gene modification.

A. N.-S. Mak, P. Bradley, R. A. Cernadas, A. J. Bogdanove, B. L. Stoddard. The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target. Science, 2012; DOI: 10.1126/science.1216211