Tuesday, May 8, 2012

Induced neural stem cells: a new tool for studying neural development and neurological disorders

Induced neural stem cells: a new tool for studying neural development and neurological disorders. Cell Research advance online publication 1 May 2012; doi: 10.1038/cr.2012.73, Guang-Hui Liu, Fei Yi, Keiichiro Suzuki, Jing Qu, Juan Carlos Izpisua Belmonte.
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing China. Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Center for Regenerative Medicine in Barcelona, 08003 Barcelona, Spain.

Recent advances in the generation of multipotent and expandable induced neural stem cells are exciting. They not only hold great promises for potential clinical applications but may also open up a new era for neural stem cell research in the near future.
alpha-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging. Bioorganic & Medicinal Chemistry Letters 21 (2011) 3693–3698, William D. Shrader, Akiko Amagata, Adam Barnes, Gregory M. Enns, Andrew Hinman, Orion Jankowski , Viktoria Kheifets, Ryo Komatsuzaki, Edgar Lee, Paul Mollard, Katsuyuki Murase, Alfredo A. Sadun, Martin Thoolen, Kieron Wesson, Guy Miller.

Keywords: Redox, Antioxidants, Quinone, Aging, Digital Biology, frataxin, Friedreich's Ataxia.