Wednesday, August 8, 2012

Neuroprotection with non-feminizing estrogen analogues: An overlooked possible therapeutic strategy

Neuroprotection with non-feminizing estrogen analogues: An overlooked possible therapeutic strategy.James W. Simpkins, Timothy E. Richardson, Kun Don Yi, Evelyn Perez, Douglas F. Covey; Hormones and Behavior, Available online 3 April 2012. http://dx.doi.org/10.1016/j.yhbeh.2012.03.013. This article is part of a Special Issue entitled Hormones & Neurotrauma.

Keywords: estrogens, estrogen receptors (ERs), neuroprotective activity, non-ER mechanisms, synthetic non-feminizing estrogens, phenolic, Friedreich's Ataxia, cell model, oxidative stress, Hormone therapy.

Unintended effects of orphan product designation for rare neurological diseases

Unintended effects of orphan product designation for rare neurological diseases, Sinéad M Murphy, Araya Puwanant and Robert C. Griggs, the CINCH IHC Consortia of the Rare Disease Clinical Research Network Unintended effects of orphan product designation for rare neurological diseases. Annals of Neurology, Accepted manuscript online: 22 JUN 2012 03:53AM EST | DOI: 10.1002/ana.23672.