Tuesday, August 28, 2012

"SILEC: A new tool to study mitochondrial and metabolic disease"

"SILEC: A new tool to study mitochondrial and metabolic disease" . Sankha S Basu, University of Pennsylvania (January 1, 2012). Dissertations available from ProQuest. Paper AAI3508967. http://repository.upenn.edu/dissertations/AAI3508967

Keywords: Coenzyme A (CoA), CoA thioesters, Stable Isotope Labeling with Essential nutrients in Cell culture (SILEC), [13C15N]-pantothenate, glutathione-CoA (CoASSG), Friedreich's Ataxia (FA), frataxin, novel biomarkers.

A Review of Friedreich Ataxia Clinical Trial Results

A Review of Friedreich Ataxia Clinical Trial Results; Susan L. Perlman, MD; J Child Neurol September 2012 vol. 27 no. 9 1217-1222, doi: 10.1177/0883073812453872

Keywords: therapeutic agents, Friedreich ataxia research pipeline (http://www.curefa.org/pipeline.html), frataxin gene, ClinicalTrials.gov, translational and clinical research.