Wednesday, December 11, 2013

Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells

Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells. Yee-Ki Lee, Philip Wing-Lok Ho, Revital Schick, Yee-Man Lau, Wing-Hon Lai, Ting Zhou, Yanhua Li, Kwong-Man Ng, Shu-Leung HO, Miguel Angel Esteban,
Ofer Binah, Hung-Fat Tse, Chung-Wah Siu; Pflügers Archiv - European Journal of Physiology, December 2013

Keywords: Friedreich ataxia (FRDA), hypertrophic cardiomyopathy, frataxin, FRDA-cardiac cellular models, iron homeostasis, calcium homeostasis, contractile force.

REGIONAL SIDEROSIS: A NEW CHALLENGE FOR IRON CHELATION THERAPY

REGIONAL SIDEROSIS: A NEW CHALLENGE FOR IRON CHELATION THERAPY. Cabantchik Zvi Ioav, Munnich Arnold, Youdim Moussa B., Devos David; Frontiers in Pharmacology, Paper pending published: 09 Dec 2013

Keywords: Iron, chelation, neurodegeneration, Anemia, Friedreich Ataxia, Parkinson Disease, deferiprone