Clinical Trial: Biomarkers in Friedreich's Ataxia ClinicalTrials.gov Identifier: NCT02497534. First received: July 7, 2015
Sponsor: University of Florida
The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.
This study is not yet open for participant recruitment.
Wednesday, July 15, 2015
Regional Cerebral Disease Progression in Friedreich's Ataxia: A Longitudinal Diffusion Tensor Imaging Study
Regional Cerebral Disease Progression in Friedreich's Ataxia: A Longitudinal Diffusion Tensor Imaging Study. Mascalchi, M., Toschi, N., Giannelli, M., Ginestroni, A., Della Nave, R., Tessa, C., Piacentini, S., Dotti, M. T., Aiello, M., Nicolai, E., Soricelli, A., Salvi, F. and Diciotti, S., Journal of Neuroimaging.(2015) doi: 10.1111/jon.12270
DTI can track brain microstructural changes in FRDA and can be considered a potential biomarker of disease progression.
DTI can track brain microstructural changes in FRDA and can be considered a potential biomarker of disease progression.
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