Monday, October 5, 2015

Pathology of Intercalated Discs in Friedreich Cardiomyopathy

R. Liane Ramirez, MS; Alyssa B. Becker, BA; Joseph E. Mazurkiewicz, PhD; Paul J. Feustel, PhD; Benjamin B. Gelman, MD, PhD; Arnulf H. Koeppen, MD, J Am Coll Cardiol. 2015;66(15):1739-1740. doi:10.1016/j.jacc.2015.06.1355

The underlying mutation in FA causes frataxin deficiency, which may adversely affect ICDs and GJs before the onset of heart disease and perhaps prenatally.