Tuesday, April 17, 2018

Could statins ease deadly heart condition in rare neuromuscular disease?

AAS and EurekAlert, Public Release: 17-Apr-2018.  University of Pennsylvania School of Medicine.
PHILADELPHIA - In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol-lowering drug increased a precursor of HDL (high-density lipoprotein), the "good cholesterol," according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania. Statins may be able to help Friedreich's ataxia patients increase their naturally low ApoA-I levels and so increase their HDL levels, which might help prevent heart disease.