Tuesday, December 10, 2019

NAD+ and Exercise in FA (ExRx in FA)

ClinicalTrials.gov Identifier: NCT04192136. December 10, 2019 Children's Hospital of Philadelphia.

Randomized, placebo-controlled trial with a 2x2 factorial design testing the effects of an NAD+ precursor (NR) and exercise on VO2max and Si in Friedreich's Ataxia (FA).
The primary objective of this research is to measure the effect of combination administration (NR + exercise) on aerobic capacity (VO2max) in FA. A key secondary objective is to measure the effect of combination administration (NR + exercise) on glucose homeostasis (Si) in FA.