Monash University will launch a new study about Friedreich's ataxia
"This project will enable both clinical and quantified gait and upper limb kinematic assessment and may provide a sensitive measure of functional change in FRDA against which the efficacy of novel interventions can be tested down the track".
Friedreich Ataxia and close related scientific news. Topics related to rare diseases.
Saturday, April 16, 2011
Infectious delivery and long-term persistence of transgene expression in the brain by a 135-kb iBAC-FXN genomic DNA expression vector.
Gene Therapy, 14 April 2011; doi:10.1038/gt.2011.45.
Gimenez-Cassina A, Wade-Martins R, Gomez-Sebastian S, Corona JC, Lim F, Diaz-Nido J.
Department of Molecular Neurobiology, Centro de Biología Molecular Severo Ochoa, Cantoblanco, Spain.
Keywords: FRDA, gene-based therapies, long-term persistent transgene expression, entire 135 kb FXN genomic DNA locus, bacterial artificial chromosome (iBAC), herpes simplex virus type 1 (HSV-1), -based vector.
Gimenez-Cassina A, Wade-Martins R, Gomez-Sebastian S, Corona JC, Lim F, Diaz-Nido J.
Department of Molecular Neurobiology, Centro de Biología Molecular Severo Ochoa, Cantoblanco, Spain.
Keywords: FRDA, gene-based therapies, long-term persistent transgene expression, entire 135 kb FXN genomic DNA locus, bacterial artificial chromosome (iBAC), herpes simplex virus type 1 (HSV-1), -based vector.