Synthesis of Benzoquinone Antioxidants and a Bleomycin Disaccharide Library. Mathilakathu Madathil, Manikandadas (Author) / Hecht, Sidney M (Advisor) / Rose, Seth (Committee member) / Woodbury, Neal (Committee member) / Arizona State University (Publisher).; Doctoral Dissertation, ASU Electronic Dissertations and Theses (2013)
The synthesized 5-amino-3-tridecyl-1,4-benzoquinone antioxidants were tested for their ability to protect Friedreich's ataxia (FRDA) lymphocytes from induced oxidative stress. Some of the analogues synthesized conferred cytoprotection in a dose-dependent manner in FRDA lymphocytes at micromolar concentrations.
FULL TEXT PDF
Friedreich Ataxia and close related scientific news. Topics related to rare diseases.
Tuesday, March 26, 2013
Assessment of upper limb function in young Friedreich ataxia patients compared to control subjects using a new three-dimensional kinematic protocol
Assessment of upper limb function in young Friedreich ataxia patients compared to control subjects using a new three-dimensional kinematic protocol.
Nathalie Maurel, Amadou Diop, Arnaud Gouelle, Corinne Alberti, Isabelle Husson; Clinical Biomechanics, Available online 26 March 2013. http://dx.doi.org/10.1016/j.clinbiomech.2013.02.007
Keywords: Friedreich ataxia, Evaluation of upper limb function, Three-dimensional kinematic protocol, Reliability, Measurement errors, Discriminative ability.
Nathalie Maurel, Amadou Diop, Arnaud Gouelle, Corinne Alberti, Isabelle Husson; Clinical Biomechanics, Available online 26 March 2013. http://dx.doi.org/10.1016/j.clinbiomech.2013.02.007
Keywords: Friedreich ataxia, Evaluation of upper limb function, Three-dimensional kinematic protocol, Reliability, Measurement errors, Discriminative ability.