Sunday, January 10, 2010

Measuring the rate of progression in Friedreich ataxia: Implications for clinical trial design

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Movement Disorders, Early View (Articles online in advance of print) Published Online: 8,Jan,2010  Lisa S. Friedman, BS 1 2 3 , Jennife...
Friday, January 8, 2010

Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

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Hum Mol Genet. 2010 Jan 6. Condò I, Malisan F, Guccini I, Serio D, Rufini A, Testi R. Laboratory of Signal Transduction, Department of E...
Tuesday, January 5, 2010

Stem cells in human neurodegenerative disorders — time for clinical translation?

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Clin. Invest. 120(1): 29-40 (2010). doi:10.1172/JCI40543. (January 4, 2010) Olle Lindvall, Zaal Kokaia Keywords: Stem cell–based approac...
Thursday, December 31, 2009

Subcellular targeting strategies for drug design and delivery

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Nature Reviews Drug Discovery 9 , 29-42 (January 2010) | doi :10.1038/nrd2897 Lawrence Rajendran , ...
Tuesday, December 29, 2009

Molecular diagnostics: techniques and applications for the clinical laboratory

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Book review. Wayne Grody , UCLA School of Medicine, Los Angeles, CA, USA Professor Divisions of Medical Genetics and Molecular Pathology ...

In Vivo Fluorescent Detection of Fe-S Clusters Coordinated by Human GRX2

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Kevin G. Hoff 1 ,  2 ,  4 , ,  Stephanie J. Culler 1 ,  4 ,  Peter Q. Nguyen 2 ,  Ryan M. McGuire 3 ,  Jonathan J. Silberg 2 ,  3 , and  Ch...

Splitting Fluorescent Protein Helps Image Clusters in Live Cells

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AZoM.com Pty.Ltd Posted December 24th, 2009 Keywords: Iron-sulfur clusters, Friedreich's ataxia, sideroblastic anemia, myopath...
Friday, December 25, 2009

A structural and functional homolog supports a general role for frataxin in cellular iron chemistry

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Communication: Chem. Commun.2010, DOI: 10.1039/b911975b Wenbin Qi and J. A. Cowan Keyword:  Bacillus subtilis ,  YdhG, frataxin family, ...
Tuesday, December 22, 2009

Safety and Efficacy Study of A0001 in Subjects With Friedreich's Ataxia

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This study is currently recruiting participants. Verified by Penwest Pharmaceuticals Co., December 2009 First Received: December 17, 200...
Sunday, December 20, 2009

Age and Dietary Iron Affect Expression of Genes Involved in Iron Acquisition and Homeostasis in Young Pigs.

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J Nutr. 2009 Dec 16. [Epub ahead of print] Hansen SL , Trakooljul N , Spears JW , Liu HC . Department of Animal Science, North Carolina ...