Friday, August 20, 2010

Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2

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Li K, Singh A, Crooks DR, Dai X, Cong Z, et al. 2010 . PLoS ONE 5(8): e12286. doi:10.1371/journal.pone.0012286 OPEN ACCESS Abstract...
Wednesday, August 18, 2010

H MR Spectroscopy in Friedreich's Ataxia and Ataxia with Oculomotor Apraxia Type 2.

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Brain Res. 2010 Aug 13. [Epub ahead of print] Iltis I, Hutter D, Bushara KO, Clark HB, Gross M, Eberly LE, Gomez CM, Oz G. Center for Mag...
Saturday, August 14, 2010

First half report 2010 - Lundbeck

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Lu AA24493 is in clinical phase II in the treatment of Friedreich's ataxia and in clinical phase I in the treatment of acute ischaemic ...

Santhera Obtains European Patent for Use of Catena®/Sovrima®

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Liestal, Switzerland, August 13, 2010 - Santhera Pharmaceuticals (SIX: SANN) announced today that the European Patent Office granted patent...
Wednesday, August 11, 2010

Friedreich’s Ataxia Induced Pluripotent Stem Cells Recapitulate GAA•TTC Triplet-Repeat Instability

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NCBI, Public on Jul 02, 2010 Experiment type: Expression profiling by array Keywords: Friedreich’s ataxia (FRDA), GAA•TTC trinucleotide ...

A Phase 3, Double-blind, Placebo-Controlled Trial of Idebenone in Friedreich Ataxia

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Arch Neurol.  2010;67(8):941-947. doi:10.1001/archneurol.2010.168 David R. Lynch, MD, PhD ; Susan L. Perlman, MD ; Thomas Meier, PhD   ...
Monday, August 9, 2010

Automated quantitative gait analysis in animal models of movement disorders

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BMC Neuroscience 2010, 11:92doi:10.1186/1471-2202-11-92 Caroline Vandeputte, Jean-Marc Taymans, Cindy Casteels, Frea Coun, Yicheng Ni, Koe...

Erythropoiesis and iron sulfur cluster biogenesis

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Advances in Hematology, Received 1 March 2010; Revised 4 June 2010; Accepted 2 August 2010 Hong Ye and Tracey A. Rouault OPEN ACCES FU...
Wednesday, August 4, 2010

Aluminum induces neurodegeneration and its toxicity arises from increased iron accumulation and reactive oxygen species (ROS) production.

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Neurobiol Aging. 2010 Jul 29. Wu Z, Du Y, Xue H, Wu Y, Zhou B. State Key Laboratory of Biomembrane and Membrane Biotechnology, School of ...

A rapid, noninvasive immunoassay for frataxin: Utility in assessment of Friedreich ataxia.

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Mol Genet Metab. 2010 Jul 8. [Epub ahead of print] Deutsch EC, Santani AB, Perlman SL, Farmer JM, Stolle CA, Marusich MF, Lynch DR. Depar...