Tuesday, December 7, 2010

Large-scale in silico modeling of metabolic interactions between cell types in the human brain

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Nature Biotechnology, Year published:(2010), DOI: doi:10.1038/nbt.1711 Nathan E Lewis, Gunnar Schramm, Aarash Bordbar, Jan Schellenberger,...
Monday, December 6, 2010

Taking the lottery out of gene therapy

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NEW SCIENTIST HEALTH ,Magazine issue 2789 GENE therapy should become a more exact science thanks to the discovery that it is possible to p...

Catalysis and Mechanistic Insights into Sirtuin Activation.

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Chembiochem. 2010 Nov 9. [Epub ahead of print]  Dittenhafer-Reed KE, Feldman JL, Denu JM. Department of Biomolecular Chemistry, School of M...

Repeat expansion affects both transcription initiation and elongation in friedreich ataxia cells

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J Biol Chem. 2010 Dec 2. [Epub ahead of print] Kumari D, Biacsi RE, Usdin K., NIH, United States. Keywords: Expansion of a GAA·TTC-repea...
Sunday, December 5, 2010

Accelerating orphan drug development

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Nature Reviews Drug Discovery 9, 901-902 (December 2010) | doi:10.1038/nrd3340 Timothy R. Coté, Kui Xu & Anne R. Pariser "Given...
Saturday, December 4, 2010

The Neuropathology of Late-Onset Friedreich's Ataxia.

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Cerebellum. 2010 Dec 4. [Epub ahead of print] Koeppen AH, Morral JA, McComb RD, Feustel PJ. Research Service (151), VA Medical Center, 11...
Wednesday, December 1, 2010

Mitochondrial Fe-S cluster biogenesis, frataxin and the modulation of susceptibility to drug-induced cardiomyopathy

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Aging (Albany NY). 2010 Nov 27. Michael N. Sack NHLBI Center for Molecular Medicine, National Institutes of Health, Bethesda, MD 20892, US...
Monday, November 29, 2010

The mitochondrial protein frataxin is essential for heme biosynthesis in plants

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FEBS Journal, Accepted Article (Accepted, unedited articles published online for future issues) DOI: 10.1111/j.1742-4658.2010.07968.x Mar...
Friday, November 26, 2010

Superior Cerebellar Peduncle Atrophy in Friedreich's Ataxia Correlates with Disease Symptoms.

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Cerebellum. 2010 Nov 24. Akhlaghi H, Corben L, Georgiou-Karistianis N, Bradshaw J, Storey E, Delatycki MB, Egan GF. Florey Neurosciences ...
Thursday, November 25, 2010

Feasibility of Implantable Cardioverter Defibrillator Treatment in Five Patients With Familial Friedreich's Ataxia—A Case Series

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Artificial Organs, Volume 34, Issue 11, pages 1061–1065, November 2010, DOI: 10.1111/j.1525-1594.2010.01140.x Keywords: Friedreich's a...