Wednesday, April 20, 2011

Spinocerebellar degenerations.

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Handb Clin Neurol. 2011;100:113-40. Perlman SL. Keywords: spinocerebellar ataxias (SCA), cerebellum, hyperkinetic movements, dominant at...
Tuesday, April 19, 2011

A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress

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BMC Systems Biology 2011, 5:51doi:10.1186/1752-0509-5-51 Fiona Achcar, Jean-Michel Camadro and Denis Mestivier Interesting tool, could b...
Monday, April 18, 2011

Sirt1 acts in association with PPARĪ± to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

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Cardiovasc Res (2011) 90 (2): 276-284. doi: 10.1093/cvr/cvq376 Ana Planavila1,2,*, Roser Iglesias1,2, Marta Giralt1,2 and Francesc Villar...

Friedreich's ataxia: Past, present and future

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doi:10.1016/j.brainresrev.2011.04.001 Daniele Marmolino, Laboratoire de Neurologie experimentale, Universite Libre de Bruxeles (ULB), Rou...
Saturday, April 16, 2011

Project title: Characterising gait and upper limb disorder in Friedreich ataxia

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Monash University will launch a new study about Friedreich's ataxia "This project will enable both clinical and quantified gait a...

Infectious delivery and long-term persistence of transgene expression in the brain by a 135-kb iBAC-FXN genomic DNA expression vector.

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Gene Therapy, 14 April 2011; doi:10.1038/gt.2011.45. Gimenez-Cassina A, Wade-Martins R, Gomez-Sebastian S, Corona JC, Lim F, Diaz-Nido J. ...
Tuesday, April 12, 2011

Intellect Neurosciences Files Orphan Drug Application in the United States for Its Clinical Candidate OX1 for the Treatment of Friedreich's Ataxia

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NEW YORK, April 12, 2011 (GLOBE NEWSWIRE) -- Intellect Neurosciences, Inc. announced today that it has filed an orphan drug application with...
Friday, April 8, 2011

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

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Curr Alzheimer Res. 2011 Apr 6. Reddy PH, Reddy TP. Neurogenetics Laboratory, Division of Neuroscience, Oregon National Primate Research ...
Thursday, April 7, 2011

New Method Delivers Drug to the Brain

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Deliver complex drug into the the CNS is a challenge, the CNS is strongly protected by the BBB, and many substances with therapeutic high po...

Mitochondria regulate autophagy by conserved signalling pathways

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The EMBO Journal advance online publication 5 April 2011; doi:10.1038/emboj.2011.104 Martin Graef and Jodi Nunnari, Department of Molecul...