Sunday, May 8, 2011

Idebenone Induces Apoptotic Cell Death in the Human Dopaminergic Neuroblastoma SHSY-5Y Cells.

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Neurotox Res. 2011 May 3. [Epub ahead of print] Tai KK, Pham L, Truong DD. The Parkinson's and Movement Disorder Research Laboratory...
Wednesday, May 4, 2011

Estrogen Protection in Friedreich's Ataxia Skin Fibroblasts

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Endocrinology, doi:10.1210/en.2011-0184, published online on May 3, 2011 Timothy E. Richardson, Shao-Hua Yang, Yi Wen and James W. Simpkin...

The heart in Friedreich's Ataxia: Basic findings and clinical implications

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Progress in Pediatric Cardiology - May 2011 (Vol. 31, Issue 2, Pages 103-109, DOI: 10.1016/j.ppedcard.2011.02.007) R. Mark Payne Riley H...
Tuesday, May 3, 2011

Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons

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Genome Res. Published in Advance April 5, 2011, doi: 10.1101/gr.112755.110 Kazuya Iwamoto 1,2,7,8, Miki Bundo 1,2,7, Junko Ueda 1, Michael...
Sunday, May 1, 2011

Sleep disorders in cerebellar ataxias

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Arq. Neuro-Psiquiatr. vol.69 no.2a São Paulo Apr. 2011, doi: 10.1590/S0004-282X2011000200021 José L. Pedroso; Pedro Braga-Neto; André C. F...
Friday, April 29, 2011

Silencing of frataxin gene expression triggers p53-dependent apoptosis in human neuron-like cells

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Hum. Mol. Genet. (2011) doi: 10.1093/hmg/ddr187 Gloria M. Palomo 1,2, Toñi Cerrato 1,2, Ricardo Gargini1 and Javier Díaz-Nido 1,2 1 Depa...

European regulation on orphan medicinal products: 10 years of experience and future perspectives

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Nature Reviews Drug Discovery 10 , 341-349 (May 2011) | doi :10.1038/nrd3445 The Committee for Orphan Medicinal Products and the European...
Thursday, April 28, 2011

Special issue of Nature Reviews on Gene-Based Therapies

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State-of-the-art gene-based therapies: the road ahead Nature Reviews Genetics 12, 316-328 (May 2011) | doi:10.1038/nrg2971 (If you want ...
Wednesday, April 27, 2011

Los vectores herpesvirales portadores de genes completos aseguran la persistencia de la expresión génica a largo plazo en ensayos de terapia génica en modelos animales.

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Los vectores herpesvirales portadores de genes completos aseguran la persistencia de la expresión génica a largo plazo en ensayos de terapia...

Herpes viral vectors carrying complete genes ensure long-term gene expression persistence in animal models of gene therapy trials.

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Press release: Herpes viral vectors carrying complete genes ensure long-term gene expression persistence in animal models of gene therapy tr...