Thursday, June 28, 2012

A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial

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A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial . Lynch, D. R., Willi, S. M., Wilson, R. B., Cottic...

Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia.

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Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated wit...
Monday, June 18, 2012

Oxidative stress inhibits axonal transport: implications for neurodegenerative diseases

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Oxidative stress inhibits axonal transport: implications for neurodegenerative diseases . Cheng Fang, Dennis Bourdette and Gary Banker. Mole...
Saturday, June 16, 2012

Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells

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Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells . Sophie Lefevre, Caroli...

Iron and neurodegeneration: from cellular homeostasis to disease.

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Iron and neurodegeneration: from cellular homeostasis to disease. Batista-Nascimento L, Pimentel C, Andrade Menezes R, Rodrigues-Pousada C....

A generalizable pre-clinical research approach for orphan disease therapy

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A generalizable pre-clinical research approach for orphan disease therapy. Review. Beaulieu CL, Samuels ME, Ekins S, McMaster CR, Edwards AM...
Wednesday, June 13, 2012

Stem Cell Therapy Shows Prospects For Severe Neurological Diseases

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ENS 2012. "Stem Cell Therapy Shows Prospects For Severe Neurological Diseases." Medical News Today. MediLexicon, Intl., 13 Jun. 20...

Complete FXN Deletion in a Patient with Friedreich's Ataxia

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Complete FXN Deletion in a Patient with Friedreich's Ataxia . Ans M.W. van den Ouweland, Rick van Minkelen, Galhana M. Bolman, Cokkie H...
Monday, June 11, 2012

Nanotechnology—novel therapeutics for CNS disorders

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Nanotechnology—novel therapeutics for CNS disorders , Review. Maya Srikanth & John A. KesslerNature Reviews Neurology 8, 307-318 (June 2...
Thursday, June 7, 2012

Longitudinal change in dysarthria associated with Friedreich ataxia: a potential clinical endpoint.

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Longitudinal change in dysarthria associated with Friedreich ataxia: a potential clinical endpoint. Rosen KM, Folker JE, Vogel AP, Corben LA...