Saturday, August 11, 2012

Iron-Sulfur Cluster Synthesis, Iron Homeostasis and Oxidative Stress in Friedreich Ataxia

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Iron-Sulfur Cluster Synthesis, Iron Homeostasis and Oxidative Stress in Friedreich Ataxia ; Rachael A. Vaubel, Grazia Isaya; Molecular and C...

The Essential Iron-Sulfur Protein Rli1 is an Important Target Accounting for Inhibition of Cell Growth by Reactive Oxygen Species

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The Essential Iron-Sulfur Protein Rli1 is an Important Target Accounting for Inhibition of Cell Growth by Reactive Oxygen Species .Alhebshi ...

Role of frataxin in erythropoietin- and carbamoylated erythropoietin- mediated neuroprotective effects in the mouse retina after acute retinal ischemia/reperfusion in vivo

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Role of frataxin in erythropoietin- and carbamoylated erythropoietin- mediated neuroprotective effects in the mouse retina after acute retin...

Quantitative Analysis to Guide Orphan Drug Development

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Quantitative Analysis to Guide Orphan Drug Development .L J Lesko. Clinical Pharmacology & Therapeutics (2012); 92 2, 258–261. doi:10.10...
Wednesday, August 8, 2012

Neuroprotection with non-feminizing estrogen analogues: An overlooked possible therapeutic strategy

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Neuroprotection with non-feminizing estrogen analogues: An overlooked possible therapeutic strategy .James W. Simpkins, Timothy E. Richardso...

Unintended effects of orphan product designation for rare neurological diseases

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Unintended effects of orphan product designation for rare neurological diseases , Sinéad M Murphy, Araya Puwanant and Robert C. Griggs, the ...
Tuesday, August 7, 2012

Epigenetic mechanisms in neurological disease

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Epigenetic mechanisms in neurological disease . Mira Jakovcevski & Schahram Akbarian;Nature Medicine 18, 1194–1204(2012) doi:10.1038/nm....
Saturday, August 4, 2012

Childhood Ataxia: Clinical Features, Pathogenesis, Key Unanswered Questions, and Future Directions.

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Childhood Ataxia: Clinical Features, Pathogenesis, Key Unanswered Questions, and Future Directions. Ashley CN, Hoang KD, Lynch DR, Perlman S...

The p53-depen dent expression of frataxin controls 5-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photo-damage in cancerous cells

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The p53-depen dent expression of frataxin controls 5-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photo-damage in...
Wednesday, August 1, 2012

Ethical Considerations in Orphan Drug Approval and Use

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Ethical Considerations in Orphan Drug Approval and Use . A S Kesselheim. Clinical Pharmacology & Therapeutics (2012); 92 2, 153–155. doi...