Friday, November 30, 2012

Synthesis and Biological Activities of N-(3-Carboxylpropyl)-5-amino-2-hydroxy-3-tridecyl-1,4-benzoquinone and Analogues.

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Synthesis and Biological Activities of N-(3-Carboxylpropyl)-5-amino-2-hydroxy-3-tridecyl-1,4-benzoquinone and Analogues. Madathil MM, Khdour...
Wednesday, November 28, 2012

The mitochondrial protein frataxin is downregulated in hemodialysis patients.

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The mitochondrial protein frataxin is downregulated in hemodialysis patients. Hasuike Y, Nagai T, Yorifuji S, Tanaka S, Matsumoto A, Yahiro ...
Friday, November 23, 2012

Novel Therapeutic Challenges in Cerebellar Diseases

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Novel Therapeutic Challenges in Cerebellar Diseases. Dr. Antoni Matilla-Dueñas, Dr. Carme Serrano, Dr. Yerko Ivánovic, Dr. Ramiro Alvarez,...
Wednesday, November 21, 2012

Characterizing POLG Ataxia: Clinics, Electrophysiology and Imaging.

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Characterizing POLG Ataxia: Clinics, Electrophysiology and Imaging. Synofzik M, Srulijes K, Godau J, Berg D, Schöls L; Cerebellum (London,...
Tuesday, November 20, 2012

Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia

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Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia . Megan Whitnall, Yohan Suryo Rahmanto, Mich...

Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA·TTC) associated with Friedreich's ataxia

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Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA·TTC) associated with Friedreich...
Monday, November 19, 2012

Assembly Factors of Human Mitochondrial Respiratory Chain Complexes: Physiology and Pathophysiology

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Assembly Factors of Human Mitochondrial Respiratory Chain Complexes: Physiology and Pathophysiology . Daniele Ghezzi, Massimo Zeviani; Mito...
Friday, November 16, 2012

Safety and Efficacy of EPI-743 in Patients With Friedreich's Ataxia

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Safety and Efficacy of EPI-743 in Patients With Friedreich's Ataxia . The purpose of this study is to examine the effects of EPI-743 ...
Thursday, November 15, 2012

EPI-743 Phase 2B Friedreich Ataxia clinical trial to be initiated

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EPI-743 Phase 2B Friedreich Ataxia clinical trial to be initiated . Friedreich’s Ataxia Research Alliance (FARA) Press release. Downingtown,...

Adaptive Clinical Trials in Orphan Drug Development

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Adaptive Clinical Trials in Orphan Drug Development . Authored by James Sheppard. Liftstream Life Science Newsletter The benefit to compan...