Tuesday, August 18, 2015

PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids

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Daniel Oropeza, Nathalie Jouvet, Khalil Bouyakdan, Gabrielle Perron, Lea-Jeanne Ringuette, Louis H. Philipson, Robert S. Kiss, Vincent Poito...

Retrotope announces open enrollment for Friedreich's ataxia clinical trial

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LOS ALTOS, Calif., Aug. 17, 2015 /PRNewswire/ -- Retrotope announces the opening of enrollment for a 28-day, first-in-human, randomized, ...

The case of a missing QRS complex

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Eric A. Meyerowitz, Ralph J. Verdino, The case of a missing QRS complex, Journal of Electrocardiology, Available online 8 August 2015, ISSN ...

Benefits of exercise in neurodegenerative diseases

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By a lot of personal experiences explained by many affected by Friedreich's ataxia it is well known that exercise is beneficial to maint...
Monday, August 17, 2015

Idebenone Protects against Oxidized Low Density Lipoprotein Induced Mitochondrial Dysfunction in Vascular Endothelial Cells via GSK3β/β-catenin signaling pathways

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Pengfei Lin, Junling Liu, Ming Ren, Kunqian Ji, Ling Li, Bin Zhang, Yaoqin Gong, Chuanzhu Yan, Idebenone Protects against Oxidized Low Densi...

Intel just open sourced Stephen Hawking’s speech system and it’s a .NET 4.5 WinForms app that you can try for yourself

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Mansib Rahman, Canadian Developer Connection. 14 Aug 2015 As we all know, the venerable physicist Professor Stephen Hawking is unable to t...

Nrf2—a therapeutic target for the treatment of neurodegenerative diseases

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Nrf2—a therapeutic target for the treatment of neurodegenerative diseases . Delinda A. Johnson, Jeffrey A. Johnson, Free Radical Biology and...
Wednesday, August 12, 2015

PATENT: SMALL MOLECULE ACTIVATORS OF MITOCHONDRIAL FUNCTION

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NEW PATENT: SMALL MOLECULE ACTIVATORS OF MITOCHONDRIAL FUNCTION. Inventor(s): WILSON ROBERT B [US]; COTTICELLI MARIA GRAZIA [US]; BENEDETT...
Saturday, August 8, 2015

Key Patent Granted For AAVLife’s Gene-Therapy Program to Treat Cardiomyopathy in Friedreich’s Ataxia

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Key Patent Granted For AAVLife’s Gene-Therapy Program to Treat Cardiomyopathy in Friedreich’s Ataxia . BUSINESS WIRE, August 05, 2015 The ...
Monday, August 3, 2015

The quality of economic evaluations of ultra-orphan drugs in Europe – a systematic review

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The quality of economic evaluations of ultra-orphan drugs in Europe – a systematic review . Y. Schuller, C. E. M. Hollak and M. Biegstraaten...