Wednesday, April 27, 2016

Genome Engineering with TALE and CRISPR Systems in Neuroscience

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Han B. Lee, Brynn N. Sundberg, Ashley N. Sigafoos, and Karl J. Clark. Front Genet. 2016; 7: 47. doi: 10.3389/fgene.2016.00047 OPEN ACCESS ...
Tuesday, April 26, 2016

Neurodegenerative diseases and therapeutic strategies using iron chelators

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Roberta J. Ward, David T. Dexter, Robert R. Crichton, Journal of Trace Elements in Medicine and Biology, Volume 31, July 2015, Pages 267-273...
Monday, April 25, 2016

Dual Role of ROS as Signal and Stress Agents: Iron Tips the Balance in favor of Toxic Effects

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Elena Gammella, Stefania Recalcati, and Gaetano Cairo. Oxidative Medicine and Cellular Longevity, Volume 2016 (2016), Article ID 8629024, 9 ...
Sunday, April 24, 2016

Time-resolved functional analysis of acute impairment of frataxin expression in an inducible cell model of Friedreich ataxia

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Dörte Poburski, Josefine Barbara Boerner, Michel Koenig, Michael Ristow, René Thierbach. Biology Open 2016 : doi: 10.1242/bio.017004 OPEN ...
Saturday, April 23, 2016

Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function

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Noemí Esteras, Albena T. Dinkova-Kostova, Andrey Y. Abramov. Biological Chemistry. Volume 397, Issue 5, Pages 383–400, ISSN (Online) 1437-43...
Friday, April 22, 2016

Cardiac Serum Biomarkers in Friedreich Ataxia May Reflect Fibrosis, Myocyte Injury, and Degree of Hypertrophy

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C. Bui, R.B. Wilson, D.R. Lynch, J.W. Rossano, O. Elci, K.Y. Lin, The Journal of Heart and Lung Transplantation, Volume 35, Issue 4, Supplem...
Thursday, April 21, 2016

Abundance and Significance of Iron, Zinc, Copper, and Calcium in the Hearts of Patients with Friedreich Ataxia

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Pamela C. Kruger, Karl X. Yang, Patrick J. Parsons, Alyssa B. Becker, Paul J. Feustel, Arnulf H. Koeppen. The American Journal of Cardiology...
Wednesday, April 20, 2016

Idebenone in Friedreich ataxia and Leber’s hereditary optic neuropathy: close mechanisms, similar therapy?

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Manuel Schiff, Pierre Rustin. Brain (2016) aww085 DOI: 10.1093/brain/aww085 First published online: 19 April 2016 "Yet despite these...
Tuesday, April 19, 2016

Plasma circulating cell-free mitochondrial DNA in the assessment of Friedreich's ataxia

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Subrahamanyam Dantham, Achal K. Srivastava, Sheffali Gulati, Moganty R. Rajeswari, Journal of the Neurological Sciences, Available online 14...
Monday, April 18, 2016

Two different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich ataxia

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Belén Mollá, Fátima Riveiro, Arantxa Bolinches-Amorós, Diana C. Muñoz-Lasso, Francesc Palau, Pilar González-Cabo. Disease Models and Mechani...