Friday, March 31, 2017

Longitudinal Gait and Balance Decline in Friedreich’s Ataxia: A Pilot Study

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Theresa A. Zesiewicz, Jeannie B. Stephenson, Seok Hun Kim, Kelly L. Sullivan, Israt Jahan, Yangxin Huang, Jason L. Salemi, Lynn Wecker, Jess...
Thursday, March 30, 2017

Ferroptosis Inhibition: Mechanisms and Opportunities

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Jose Pedro Friedmann Angeli, Ron Shah, Derek A. Pratt, Marcus Conrad, Trends in Pharmacological Sciences, Available online 28 March 2017, IS...
Wednesday, March 29, 2017

Individualized exergame training improves postural control in advanced degenerative spinocerebellar ataxia: A rater-blinded, intra-individually controlled trial

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Conny Schatton, Matthis Synofzik, Zofia Fleszar, Martin A. Giese, Ludger Schöls, Winfried Ilg, Parkinsonism & Related Disorders, Availab...
Tuesday, March 28, 2017

Nonreplicative genomic HSV-1 derived vectors for dorsal root ganglion gene therapy of Friedreich´s ataxia

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María Ventosa Rosales, Directores de la Tesis: Filip Lim (dir. tes.) Lectura: En la Universidad Autónoma de Madrid ( España ) en 2016. Idiom...
Sunday, March 19, 2017

Mitochondrial biogenesis in neurodegeneration

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Li, P. A., Hou, X. and Hao, S. (2017), J. Neurosci. Res.. doi: 10.1002/jnr.24042 Neurodegenerative diseases, including Alzheimer's dis...
Saturday, March 18, 2017

Resveratrol regulates microglia M1/M2 polarization via PGC-1α in conditions of neuroinflammatory injury

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Xiaodong Yang, Shaoqing Xu, Yiwei Qian, Qin Xiao, Brain, Behavior, and Immunity, Available online 6 March 2017, ISSN 0889-1591, doi:10.1016/...
Friday, March 17, 2017

A wearable proprioceptive stabilizer for rehabilitation of limb and gait ataxia in hereditary cerebellar ataxias: a pilot open-labeled study

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Luca Leonardi, Maria Gabriella Aceto, Christian Marcotulli, Giuseppe Arcuria, Mariano Serrao, Francesco Pierelli, Paolo Paone, Alessandro Fi...
Thursday, March 16, 2017

Voyager Therapeutics: Advance multiple preclinical programs towards clinical trials, with the goal of filing three IND applications within the next 24-months VY-FXN01 program

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Voyager Therapeutics Reports Fourth Quarter and Full Year 2016 Financial Results and Corporate Highlights. CAMBRIDGE, Mass., March 15, 2017 ...
Tuesday, March 14, 2017

Affordable orphan drugs: a role for not-for-profit organizations

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Davies, E. H., Fulton, E., Brook, D., and Hughes, D. A. (2017). Br J Clin Pharmacol, doi: 10.1111/bcp.13240. Although the regulatory steps...
Monday, March 13, 2017

Early-Onset Friedreich's Ataxia With Oculomotor Apraxia

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Amene Saghazadeh, Sina Hafizi, Firouzeh Hosseini, Mahmoud Reza Ashrafi, Nima Rezaei; Acta Medica Iranica 2017. 55(2):128-130. Here we desc...