Thursday, August 17, 2017

Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics

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Madhu M. Kanchi, Muthu K. Shanmugam, Grishma Rane, Gautam Sethi, Alan P. Kumar, Drug Discovery Today, 2017, ISSN 1359-6446, doi:10.1016/j.d...

Targeting Mitochondrial Dysfunction in Neurodegenerative Disease

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The Dana Foundation. By Kayt Sukel, August 15, 2017 It’s long been known that the brain is an energy glutton: Most estimates suggest that...
Wednesday, August 16, 2017

Mechanisms of unexpected death and autopsy findings in Friedreich ataxia

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Roger W Byard, , John D Gilbert; Medicine, Science and the Law, First published date: August-13-2017, Doi:10.1177/0025802417723809 A 36-ye...
Tuesday, August 15, 2017

FDA Confirms That Use of mFARS as Primary Endpoint in Part 2 of the MOXIe Trial Can Support Approval of Omaveloxolone in Friedreich’s Ataxia

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RVING, Texas, Aug. 14, 2017 (GLOBE NEWSWIRE) -- Reata Pharmaceuticals, Inc. (Nasdaq:RETA) (“Reata” or the “Company”), a clinical-stage bioph...
Monday, August 14, 2017

Mitochondrial biogenesis and neural differentiation of human iPSC is modulated by idebenone in a developmental stage-dependent manner

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J. Augustyniak, J. Lenart, M. Zychowicz, P. P. Stepien, L. Buzanska. Biogerontology (2017) 18: 665. doi:10.1007/s10522-017-9718-4 Idebenon...
Friday, August 11, 2017

Reversible axonal dystrophy by calcium modulation in frataxin-deficient sensory neurons of YG8R mice

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Belén Mollá, Diana C. Muñoz-Lasso, Fatima Riveiro1, Arantxa Bolinches-Amorós, Federico V. Pallardó, Angel Fernandez-Vilata, Maria D. Vaya,...
Thursday, August 10, 2017

Heart and Nervous System Pathology in Compound Heterozygous Friedreich Ataxia

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Alyssa B. Becker, BA Jiang Qian, MD, PhD Benjamin B. Gelman, MD, PhD Michele Yang, MD Peter Bauer, MD Arnulf H. Koeppen, MD; Journal of Neu...
Saturday, August 5, 2017

Mitochondrial dysfunction in the neuro-degenerative and cardio-degenerative disease, Friedreich's ataxia

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Shannon Chiang, Danuta S. Kalinowski, Patric J. Jansson, Des R. Richardson, Michael L.-H. Huang, Friedreich's ataxia, Neurochemistry Int...
Friday, August 4, 2017

Chondrial Announces FDA Orphan Drug Designation for CTI-1601, a Novel Investigational Technology for the Treatment of Friedreich's Ataxia

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BALA CYNWYD, Pa., Aug. 3, 2017 /PRNewswire/ -- Chondrial Therapeutics, Inc., an emerging biotechnology company focused on the treatment of r...
Tuesday, August 1, 2017

The importance of international collaboration for rare diseases research: a European perspective

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D Julkowska, C P Austin, C M Cutillo, D Gancberg, C Hager, J Halftermeyer, A H Jonker, L P L Lau, I Norstedt, A Rath, R Schuster, E Simelyte...