Saturday, May 12, 2018

Small molecules capable of activating DNA methylation–repressed genes targeted by the p38 mitogen-activated protein kinase pathway

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Xiang Li, Erchang Shang, Qiang Dong, Yingfeng Li, Jing Zhang, Shaohua Xu, Zuodong Zhao, Wei Shao, Cong Lv, Yong Zheng, Hailin Wang, Xiaoguan...
Tuesday, May 8, 2018

Monthly update: April 6-Mai 6, 2018

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Monthly update: April 6-Mai 6, 2018 Sunday, May 6, 2018 Low-level mitochondrial heteroplasmy modulates DNA replication, glucose meta...
Sunday, May 6, 2018

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

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Misa Hirose, Paul Schilf, Yask Gupta, Kim Zarse, Axel Künstner, Anke Fähnrich, Hauke Busch, Junping Yin, Marvin N. Wright, Andreas Ziegler, ...

Advances in Biomarker-Guided Therapy for Pediatric- and Adult-Onset Neuroinflammatory Disorders: Targeting Chemokines/Cytokines

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Michael R. Pranzatelli, Front Immunol. 2018; 9: 557. Published online 2018 Apr 4. doi:10.3389/fimmu.2018.00557 The concept and recognized ...
Saturday, May 5, 2018

Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich’s Ataxia

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Omar M. Khdour, Indrajit Bandyopadhyay, Sandipan Roy Chowdhury, Nishant P. Visavadiya, Sidney M. Hecht, Bioorganic & Medicinal Chemistry...

How Orphan Drugs Became a Highly Profitable Industry

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The Scientist; By Diana Kwon | May 1, 2018 Government incentives, advances in technology, and an army of patient advocates have spun a su...
Friday, May 4, 2018

The mystery of the cerebellum: clues from experimental and clinical observations

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Charlotte Lawrenson, Martin Bares, Anita Kamondi, Andrea Kovács, Bridget Lumb, Richard Apps, Pavel Filip and Mario Manto; Cerebellum & A...

Current and Promising Therapies in Autosomal Recessive Ataxias

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Vincent Picher-Martel, Nicolas Dupre. CNS Neurol Disord Drug Targets. 2018 Apr 18. doi: 10.2174/1871527317666180419115029. [Epub ahead of pr...
Tuesday, May 1, 2018

Cerebellar contribution to locomotor behavior: A neurodevelopmental perspective

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Aaron Sathyanesan, Vittorio Gallo, Neurobiology of Learning and Memory, Available online 30 April 2018, ISSN 1074-7427, doi:10.1016/j.nlm.20...
Saturday, April 28, 2018

Clinical management of Friedreich’s Ataxia: a report of two cases

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Yannis Dionyssiotis, Athina Kapsokoulou, Anna Danopoulou, Maria Kokolaki & Athina Vadalouka; Spinal Cord Series and Casesvolume 4, Artic...