Sunday, June 3, 2018

Modelling the dorsal root ganglia using human pluripotent stem cells: A platform to study peripheral neuropathies

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Serena Viventi, Mirella Dottori, The International Journal of Biochemistry & Cell Biology, Volume 100, July 2018, Pages 61-68, ISSN 1357...
Tuesday, May 29, 2018

TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation

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Wing-Hang Tong, Nunziata Maio, De-Liang Zhang, Erika M. Palmieri, Hayden Ollivierre, Manik C. Ghosh, Daniel W. McVicar and Tracey A. Rouault...
Saturday, May 26, 2018

Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich’s ataxia patients

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Daniel Nachun, Fuying Gao, Charles Isaacs, Cassandra Strawser, Zhongan Yang, Deepika Dokuru, Victoria Van Berlo, Renee Sears, Jennifer Farme...

A missed Fe-S cluster handoff causes a metabolic shakeup

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Olivier Berteau; The Journal of Biological Chemistry 293, 8312-8313. doi: 10.1074/jbc.H118.002883 these findings hold significance for the...

Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells

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Daniel R. Crooks, Nunziata Maio§, Andrew N. Lane, Michal Jarnik, Richard M. Higashi, Ronald G. Haller, Ye Yang, Teresa W-M. Fan, W. Marston ...
Friday, May 25, 2018

Improving the analysis of composite endpoints in rare disease trials

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Martina McMenami, Anna Berglind and James M. S. Wason; Orphanet Journal of Rare Diseases 201813:81 doi:10.1186/s13023-018-0819-1 In rare d...

Biomimetic Artificial Epigenetic Code for Targeted Acetylation of Histones

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Junichi Taniguchi, Yihong Feng, Ganesh N. Pandian, Fumitaka Hashiya, Takuya Hidaka, Kaori Hashiya, Soyoung Park, Toshikazu Bando, Shinji Ito...
Sunday, May 20, 2018

Voyager Therapeutics Announces Additional Data at the American Society of Gene and Cell Therapy 2018 Annual Meeting

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CAMBRIDGE, Mass., May 18, 2018 (GLOBE NEWSWIRE) -- Voyager Therapeutics, Inc. (NASDAQ:VYGR), a clinical-stage gene therapy company focused o...
Thursday, May 17, 2018

Pediatric Ataxia: Focus on Chronic Disorders.

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Lynch DR, McCormick A, Schadt K, Kichula E.; Semin Pediatr Neurol. 2018 Apr;25:54-64. doi: 10.1016/j.spen.2018.01.001. FRDA is the most co...

DNA triplex structure, thermodynamics, and destabilisation: insight from molecular simulations

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Belinda J. Boehm, Charles Whidborne, Alexander L. Button, Tara L. Pukala and David M. Huang; Phys Chem Chem Phys. 2018 May 10. doi: 10.103...