Wednesday, January 16, 2019

Young adult with Friedreich ataxia

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Milano EG, Harries IB, Bucciarelli-Ducci C, Heart Published Online First: 15 January 2019. doi: 10.1136/heartjnl-2018-314387 Clinical intr...
Tuesday, January 15, 2019

Revealing the Superpowers of PrimPol: rescuing replicating microsatellites

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Reid, J. E., & Fischer, T. (2019). The EMBO Journal, e101298. doi:10.15252/embj.2018101298 Error‐free replication of repetitive stretc...
Monday, January 14, 2019

Ferroptosis as a novel therapeutic target for Friedreich's ataxia

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M. Grazia Cotticelli, Shujuan Xia, Daniel Lin, Taehee Lee, Leila Terrab, Peter Wipf, Donna Huryn and Robert Wilson Journal of Pharmacology ...
Sunday, January 13, 2019

Longitudinal evaluation of iron concentration and atrophy in the dentate nuclei in friedreich ataxia

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Phillip G. D. Ward PhD, Ian H. Harding PhD, Thomas G. Close PhD, Louise A. Corben PhD, Martin B. Delatycki MBBS, FRACP, PhD, Elsdon Storey D...
Saturday, January 12, 2019

Etravirine in Friedreich's ataxia: Lessons from HIV?

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Lynch DR, Schadt K1, Kichula E. Mov Disord. 2019 Jan 10. doi: 10.1002/mds.27605. [Epub ahead of print]
Friday, January 11, 2019

Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia

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Giulia Alfedi MSc, Riccardo Luffarelli MSc, Ivano Condò PhD, Giorgia Pedini MSc, Liliana Mannucci PhD, Damiano S. Massaro PhD, Monica Benini...
Wednesday, January 2, 2019

Differences in the determinants of right ventricular and regional left ventricular long-axis dysfunction in Friedreich ataxia

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Peverill RE, Donelan L, Corben LA, Delatycki MB (2018). PLoS ONE 13(12): e0209410. doi:10.1371/journal.pone.0209410 There are generalized ...
Friday, December 28, 2018

GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich Ataxia cellular models

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Yi Na Dong Emily McMillian Elisia M Clark Hong Lin David R Lynch, Human Molecular Genetics, ddy448, doi:10.1093/hmg/ddy448 Published: 26 Dec...
Monday, December 17, 2018

Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures

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Jiun-I Lai, Daniel Nachun, Lina Petrosyan, Benjamin Throesch, Erica Campau, Fuying Gao, Kristin K Baldwin, Giovanni Coppola, Joel M. Gottesf...
Saturday, December 15, 2018

Correction of half the cardiomyocytes fully rescue Friedreich Ataxia mitochondrial cardiomyopathy through cell-autonomous mechanisms

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Brahim Belbellaa, Laurence Reutenauer, Laurent Monassier, Hélène Puccio; Human Molecular Genetics, , ddy427, doi:10.1093/hmg/ddy427 Correl...