Tuesday, July 30, 2019

The neuroprotective mechanisms and effects of sulforaphane

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Klomparens EA, Ding Y.; Brain Circ 2019;5:74-83 DOI: 10.4103/bc.bc_7_19 Sulforaphane (SFN) is a phytochemical found in cruciferous vegetab...
Monday, July 29, 2019

Yeast as a Tool for Deeper Understanding of Human Manganese-Related Diseases

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Louise Thines, Antoine Deschamps, Jiri Stribny and Pierre Morsomme; Genes 2019, 10(7), 545; (Review) doi:10.3390/genes10070545 Several ma...
Saturday, July 27, 2019

The path toward using microbial metabolites as therapies

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Hélène C. Descamps, Beatrice Herrmann, Daphne Wiredu, Christoph A. Thaiss; EBioMedicine (Published by The Lancet), Volume 44, 2019, Pages 74...
Monday, July 22, 2019

New developments in pharmacotherapy for Friedreich ataxia

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Alexandra Clay, Patrick Hearle, Kim Schadt & David R. Lynch (2019) New developments in pharmacotherapy for Friedreich ataxia, Expert Opi...

Iron Hack - A symposium/hackathon focused on porphyrias, Friedreich’s ataxia, and other rare iron-related diseases [version 1; peer review: awaiting peer review]

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Gloria C. Ferreira, Jenna Oberstaller, Renée Fonseca, Thomas E. Keller, Swamy Rakesh Adapa, Justin Gibbons, Chengqi Wang, Xiaoming Liu, Chan...
Thursday, July 18, 2019

Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia

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Gottesfeld, J.M. Neurotherapeutics (2019). doi:10.1007/s13311-019-00764-x Numerous approaches are being taken to find a treatment for FRDA...
Tuesday, July 16, 2019

Oxidative post‐translational modifications in histones

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José Luis García‐Giménez, Carlos Romá‐Mateo, Federico V. Pallardó; Biofactors. 2019 Jun 11. doi: 10.1002/biof.1532. Epigenetic regulatio...
Sunday, July 14, 2019

Biointaxis busca cinco millones para culminar su fase preclínica regulatoria

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La spin off del Institut Germans Trias i Pujol (Igtp) quiere levantar once millones de euros durante los próximos cinco años para desarrolla...
Friday, July 12, 2019

The current state of biomarker research for Friedreich’s ataxia: a report from the 2018 FARA biomarker meeting

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Ian A Blair, Jennifer Farmer, Steven Hersch, Jane Larkindale, David R Lynch, Jill Napierala, Marek Napierala, R Mark Payne & Sub H Subra...
Wednesday, July 10, 2019

Evaluation of antibodies for western blot analysis of frataxin protein isoforms

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Liwei Weng, Qingqing Wang, Sixiang Yu, Xiaolu Yang, David R. Lynch, Clementina Mesaros, Ian A. Blair; Journal of Immunological Methods, 20...