Sunday, March 8, 2020

The Assessment of Upper Limb Functionality in Friedreich Ataxia via Self-Feeding Activity

›
K. D. Nguyen, L. A. Corben, P. N. Pathirana, M. K. Horne, M. B. Delatycki and D. J. Szmulewicz, IEEE Transactions on Neural Systems and Reha...
Thursday, March 5, 2020

Polyunsaturated Fatty Acid Deuteration against Neurodegeneration

›
Mikhail S. Shchepinov, Trends in Pharmacological Sciences, 2020, doi:10.1016/j.tips.2020.01.010. Regioselective deuteration that reinforce...
Wednesday, March 4, 2020

Identification of Frataxin as a regulator of ferroptosis

›
Jing Du, Yi Zhou, Yanchun Li, Jun Xia, Yongjian Chen, Sufeng Chen, Xin Wang, Weidong Sun, Tongtong Wang, Xueying Ren, Xu Wang, Yihan An, Kan...
Tuesday, March 3, 2020

An Overview of the Current State and the Future of Ataxia Treatments

›
Kimberly Tsu Kwei, Sheng-Han Kuo; Neurologic Clinics, 2020, doi:10.1016/j.ncl.2020.01.008. Keywords: Cerebellum; Ataxia; Multiple system a...
Sunday, March 1, 2020

Epigenetic regulation of clinical manifestations of Friedreich's disease

›
Nuzhny EP, Abramycheva NY, Nikolaeva NS, Ershova MV, Klyushnikov SA, Illarioshkin SN, Fedotova EY.; Zh Nevrol Psikhiatr Im S S Korsakova. 20...
Sunday, February 23, 2020

Management of Neuroinflammatory Responses to AAV-Mediated Gene Therapies for Neurodegenerative Diseases

›
Perez, B.A.; Shutterly, A.; Chan, Y.K.; Byrne, B.J.; Corti, M.; Brain Sci. 2020, 10, 119; doi:10.3390/brainsci10020119 (registering DOI) R...
Monday, February 17, 2020

A Phase 2 Clinical Trial to Test the Safety and Efficacy of Etravirine in Friedreich Ataxia Patients (FAEST1)

›
ClinicalTrials.gov Identifier: NCT04273165. February 17, 2020, Sponsor: IRCCS Eugenio Medea, Collaborator: University of Rome Tor Vergata....
Friday, February 14, 2020

Instrumented Data Exchange for Ataxia Study (IDEA)

›
ClinicalTrials.gov Identifier: NCT04268147. Sponsor: University of Chicago. Collaborators: Pfizer, Biogen, APDM Wearable Technologies. This...
Tuesday, February 11, 2020

Loss of mitochondrial localization of human FANCG causes defective FANCJ helicase

›
Sudit S Mukhopadhyay, Jagadeesh Chandra Bose K, Bishwajit Singh Kapoor, Kamal Mandal, Subhrima Ghosh, Raveendra B Mokhamatam, Sunil K Manna;...
Monday, February 10, 2020

NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis

›
Nady Braidy, Yue Liu; Experimental Gerontology, 2020, 110831, doi:10.1016/j.exger.2020.110831. While these compounds presented with a limi...