Tuesday, March 17, 2020

Enhanced production of herpes simplex virus 1 (HSV-1) amplicon vectors by gene modification and optimization of packaging cell growth medium

›
Iván Fernández-Frías, Sara Pérez-Luz, Javier Díaz-Nido, Molecular Therapy - Methods & Clinical Development, 2020, doi:10.1016/j.omtm.202...
Friday, March 13, 2020

Advances in drug therapy for mitochondrial diseases.

›
Lufei Zhang, Zhaoyong Zhang, Aisha Khan, Hui Zheng, Chao Yuan, Haishan Jiang; Annals of Translational Medicine, 01 Jan 2020, 8(1):17 DOI: 1...
Tuesday, March 10, 2020

Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis

›
Nunziata Maio, Tracey A. Rouault; Trends in Biochemical Sciences, 2020, doi:10.1016/j.tibs.2020.02.001. Structural determinations of the a...
Sunday, March 8, 2020

The Assessment of Upper Limb Functionality in Friedreich Ataxia via Self-Feeding Activity

›
K. D. Nguyen, L. A. Corben, P. N. Pathirana, M. K. Horne, M. B. Delatycki and D. J. Szmulewicz, IEEE Transactions on Neural Systems and Reha...
Thursday, March 5, 2020

Polyunsaturated Fatty Acid Deuteration against Neurodegeneration

›
Mikhail S. Shchepinov, Trends in Pharmacological Sciences, 2020, doi:10.1016/j.tips.2020.01.010. Regioselective deuteration that reinforce...
Wednesday, March 4, 2020

Identification of Frataxin as a regulator of ferroptosis

›
Jing Du, Yi Zhou, Yanchun Li, Jun Xia, Yongjian Chen, Sufeng Chen, Xin Wang, Weidong Sun, Tongtong Wang, Xueying Ren, Xu Wang, Yihan An, Kan...
Tuesday, March 3, 2020

An Overview of the Current State and the Future of Ataxia Treatments

›
Kimberly Tsu Kwei, Sheng-Han Kuo; Neurologic Clinics, 2020, doi:10.1016/j.ncl.2020.01.008. Keywords: Cerebellum; Ataxia; Multiple system a...
Sunday, March 1, 2020

Epigenetic regulation of clinical manifestations of Friedreich's disease

›
Nuzhny EP, Abramycheva NY, Nikolaeva NS, Ershova MV, Klyushnikov SA, Illarioshkin SN, Fedotova EY.; Zh Nevrol Psikhiatr Im S S Korsakova. 20...
Sunday, February 23, 2020

Management of Neuroinflammatory Responses to AAV-Mediated Gene Therapies for Neurodegenerative Diseases

›
Perez, B.A.; Shutterly, A.; Chan, Y.K.; Byrne, B.J.; Corti, M.; Brain Sci. 2020, 10, 119; doi:10.3390/brainsci10020119 (registering DOI) R...
Monday, February 17, 2020

A Phase 2 Clinical Trial to Test the Safety and Efficacy of Etravirine in Friedreich Ataxia Patients (FAEST1)

›
ClinicalTrials.gov Identifier: NCT04273165. February 17, 2020, Sponsor: IRCCS Eugenio Medea, Collaborator: University of Rome Tor Vergata....