Thursday, June 18, 2020

NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases

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Cores, Á.; Piquero, M.; Villacampa, M.; León, R.; Menéndez, J.C; Biomolecules 2020, 10, 904. doi:10.3390/biom10060904 NRF2 acts by control...
Wednesday, June 17, 2020

[Epigenetic Regulation of Clinical Manifestations of Friedreich's Disease]

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E P Nuzhny, N Yu Abramycheva, N S Nikolaeva, M V Ershova, S A Klyushnikov, S N Illarioshkin, E Yu Fedotova. Épigeneticheskaia reguliatsiia k...
Tuesday, June 16, 2020

EXERCISE MAY OFFER ‘PROFOUND’ BENEFITS FOR FRIEDREICH'S ATAXIA, RESEARCH SUGGESTS

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UVA Today. University of Virginia, June 15, 2020 Josh Barney. Yan, of UVA’s Departments of Medicine, Pharmacology and Molecular Physiology...
Monday, June 15, 2020

Substrate-dependent suppression of oxidative phosphorylation in the Frataxin-depleted heart

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Cesar Vasquez, Monika Patel, Aishwarya Sivaramakrishnan, Carmen Bekeova, Lauren Anderson-Pullinger, Nadan Wang, Erin L Seifert bioRxiv 2020...
Sunday, June 14, 2020

Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy

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Dr. Jixue Li, Dr. Yanjie Li, Dr. Jun Wang, Dr. Trevor J. Gonzalez, Dr. Aravind Asokan, Dr. Jill Napierala, and Dr. Marek Napierala; Hum Gene...
Saturday, June 13, 2020

Treatment of Dilated Cardiomyopathy in a Mouse Model of Friedreich’s Ataxia using N-acetylcysteine and Identification of Alterations in MicroRNA Expression that Could be Involved in its Pathogenesis

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S. Chiang, M.L.H. Huang, D.R. Richardson, Pharmacological Research, 2020, 104994, doi:10.1016/j.phrs.2020.104994. Deficient expression of ...
Friday, June 12, 2020

Vestibular Impact of Friedreich Ataxia in Early Onset Patients

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A Maudoux, N Teissier, M Francois, Th Van Den Abbeele, C Alberti, I Husson, S R Wiener-Vacher; Cerebellum Ataxias. 2020;7:6. Published 2020...
Thursday, June 11, 2020

A Novel Solution-Gated Graphene Transistor Biosensor for Ultrasensitive Detection of Trinucleotide Repeats

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Zhiqi Ge, Mingyu Ma, Zang Chang, Meijun Chen, Hanping He, Xiuhua Zhang and Shengfu Wang, 2020, doi:10.1039/D0AN00205D A new way to detect ...
Monday, June 8, 2020

Cerebellar cognitive disorder parallels cerebellar motor symptoms in Friedreich ataxia

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Naeije, G., Rai, M., Allaerts, N., Sjogard, M., De Tiège, X. and Pandolfo, M.; Ann Clin Transl Neurol. doi:10.1002/acn3.51079 Dentate nucl...
Saturday, June 6, 2020

HMTase Inhibitors as a Potential Epigenetic-Based Therapeutic Approach for Friedreich’s Ataxia

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Sherzai, Mursal; Valle, Adamo; Perry, Nicholas; Kalef-Ezra, Ester; Al-Mahdawi, Sahar; Pook, Mark; Sara Anjomani Virmouni. Frontiers. Collect...