Wednesday, July 22, 2020

P55 - Characterization of in vivo disposition of CTI-1601: A mitochondria targeted therapy for friedreich’s ataxia

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Eric Gonzalez, Erik Wagner, Nicholas Mess, Amy Wang, Mark Payne, David Bettoun, Elizabeth Ottinger, Bonnie Rup, Xin Xu, Drug Metabolism and ...
Tuesday, July 21, 2020

Larimar Therapeutics Announces Dosing of Patients in Third Cohort of Phase 1 SAD Trial of CTI-1601 for Treatment of Friedreich’s Ataxia

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BALA CYNWYD, Pa., July 20, 2020 (GLOBE NEWSWIRE) -- Larimar Therapeutics, Inc. (Nasdaq:LRMR), a clinical-stage biotechnology company focused...
Sunday, July 19, 2020

Safety and Efficacy of (+)-Epicatechin in Subjects with Friedreich's Ataxia: A Phase II, Open-Label, Prospective Study

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Qureshi, M. Y., Patterson, M. C., Clark, V., Johnson, J. N., Moutvic, M. A., Driscoll, S. W., Kemppainen, J. L., Huston, J., 3rd, Anderson, ...
Sunday, July 12, 2020

Stress-induced Mouse Model of the Cardiac Manifestations of Friedreich's Ataxia Corrected by AAV-mediated Gene Therapy

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Ms. Christiana Salami, Ms. Katie Jackson, Ms. Clarisse L. Jose, Mr. Laith Alyass, Mr. Georges-Ibrahim Cisse, Dr. Bishnu P De, Dr. Katie Stil...
Thursday, July 9, 2020

Compound heterozygosity for an expanded (GAA) and a (GAAGGA) repeat at FXN locus: from a diagnostic pitfall to potential clues to the pathogenesis of Friedreich ataxia

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Massimo Santoro, Alessia Perna, Piergiorgio La Rosa, Sara Petrillo, Fiorella Piemonte, Salvatore Rossi, Vittorio Riso, Tommaso Filippo Nicol...
Saturday, July 4, 2020

Analysis of Postural Control in Sitting by Pressure Mapping in Patients With Multiple Sclerosis, Spinal Cord Injury and Friedreich's Ataxia

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María Mercedes Reguera-García, Raquel Leirós-Rodríguez, Lorena Álvarez-Barrio, Beatriz Alonso-Cortés Fradejas; Preprint from Research Square...
Thursday, July 2, 2020

Medical and Paramedical Care of Patients With Cerebellar Ataxia During the COVID-19 Outbreak: Seven Practical Recommendations of the COVID 19 Cerebellum Task Force.

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Manto M, Dupre N, Hadjivassiliou M, Louis ED, Mitoma H, Molinari M, Shaikh AG, Soong B-W, Strupp M, Van Overwalle F and Schmahmann JD (2020)...
Wednesday, July 1, 2020

Feasibility and Acceptability of Lee Silverman Voice Treatment in Progressive Ataxias

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Lowit, A., Egan, A. & Hadjivassiliou, M.; Cerebellum (2020). doi:10.1007/s12311-020-01153-3 LSVT LOUD® focuses on the production of he...
Friday, June 26, 2020

Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia

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Daniel Fil, Balu K. Chacko, Robbie Conley, Xiaosen Ouyang, Jianhua Zhang, Victor M. Darley-Usmar, Aamir R. Zuberi, Cathleen M. Lutz, Marek N...
Tuesday, June 23, 2020

DNA Hypermethylation and Unstable Repeat Diseases: A Paradigm of Transcriptional Silencing to Decipher the Basis of Pathogenic Mechanisms

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Poeta, Loredana; Drongitis, Denise; Verrillo, Lucia; Miano , Maria Giuseppina; Genes 11, no. 6: 684. doi:10.3390/genes11060684 We report o...