Thursday, October 8, 2020

Recapitulating the frataxin activation mechanism in an engineered bacterial cysteine desulfurase supports the architectural switch model

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Shachin Patra, Cheng-Wei Lin, Manas K. Ghosh, Steven M. Havens, Seth A. Cory, David H. Russell, David P. Barondeau bioRxiv 2020.10.06.326603...
Tuesday, October 6, 2020

Expanding the genotype–phenotype correlation of childhood sensory polyneuropathy of genetic origin

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Samya Chakravorty, Rachel Logan, Molly J. Elson, Rebecca R. Luke & Sumit Verma; Sci Rep 10, 16184 (2020). doi:10.1038/s41598-020-73219-...
Monday, October 5, 2020

Emerging therapies in Friedreich's Ataxia

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Zesiewicz TA, Hancock J, Ghanekar SD, Kuo SH, Dohse CA, Vega J. ; Expert Rev Neurother. 2020 Sep 21:1-14. doi:10.1080/14737175.2020.1821654...
Sunday, October 4, 2020

Mechanism of Iron–Sulfur Cluster Assembly: In the Intimacy of Iron and Sulfur Encounter

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Srour, B.; Gervason, S.; Monfort, B.; D’Autréaux, B. . Inorganics 2020, 8, 55.   doi:10.3390/inorganics8100055 In this paper, we review the ...
Saturday, October 3, 2020

Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis

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Jingjing Liu, Hui He, Jing Wang, Xiaoping Guo, Hongkun Lin, Huimin Chen, Chunjie Jiang, Li Chen, Ping Yao, Yuhan Tang, Toxicology, 2020, 152...
Saturday, September 26, 2020

Home Based Tele-exercise for People With Chronic Neurological Impairments: COVID and Beyond (Telex)

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ClinicalTrials.gov Identifier: NCT04564495. To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health...

Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich’s ataxia

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Liwei Weng, Laurent Laboureur, Qingqing Wang, Lili Guo, Peining Xu, Leah Gottlieb, David R. Lynch, Clementina Mesaros & Ian A. Blair; Sc...
Thursday, September 24, 2020

IXICO joins neuroimaging consortium focused on Friedreich’s Ataxia

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24 Sep 2020. IXICO PLC (LON:IXI) said it has entered a five year collaboration with the Friedreich's Ataxia Research Alliance (FARA) to ...
Wednesday, September 16, 2020

Biomarker for Friedreich's Ataxia (BioFridA) (BioFridA)

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ClinicalTrials.gov Identifier: NCT04548921. Responsible Party: Centogene AG Rostock. Recruitment Status : Recruiting, First Posted : Septemb...
Saturday, September 12, 2020

Altered Secretome and ROS Production in Olfactory Mucosa Stem Cells Derived from Friedreich’s Ataxia Patients

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Pérez-Luz, S.; Loria, F.; Katsu-Jiménez, Y.; Oberdoerfer, D.; Yang, O.-L.; Lim, F.; Muñoz-Blanco, J.L.; Díaz-Nido, J.; Int. J. Mol. Sci. 202...