Tuesday, November 10, 2020

The Nrf2 induction prevents ferroptosis in Friedreich’s Ataxia

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Piergiorgio La Rosa, Sara Petrillo, Riccardo Turchi, Francesco Berardinelli, Tommaso Schirinzi, Gessica Vasco, Daniele Lettieri-Barbato, Mar...
Sunday, November 8, 2020

PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia

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Laura Rodríguez-Pascau, Elena Britti, Pablo Calap-Quintana, Yi Na Dong, Cristina Vergara, Fabien Delaspre, Marta Medina, Jordi Tamarit, Fede...
Friday, November 6, 2020

Electrocardiogram in Friedreich's ataxia: A short‐term surrogate endpoint for treatment efficacy

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Sandra Mastroianno MD Michele Germano MD Angela Maggio MD Raimondo Massaro MD Domenico Rosario Potenza MD Aldo Russo MD Massimo Carell...
Thursday, November 5, 2020

Effect of Mitochondrial and Cytosolic FXN Isoform Expression on Mitochondrial Dynamics and Metabolism

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Agrò, M.; Díaz-Nido, J. , Int. J. Mol. Sci. 2020, 21, 8251. doi:10.3390/ijms21218251 (registering DOI) Alternative forms of frataxin have be...
Saturday, October 31, 2020

European Investment Bank provides Minoryx with up to €25 million to support development of breakthrough therapies in orphan neurodegenerative diseases

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Press release, 30 October 2020, Barcelona.  The European Investment Bank (EIB) today announced that it has approved €25 million financing fo...

EL BANCO EUROPEO DE INVERSIONES PROPORCIONA €25M A MINORYX PARA APOYAR EL DESARROLLO DE TERAPIAS INNOVADORAS EN ENFERMEDADES RARAS NEURODEGENERATIVAS.

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Mataró (Barcelona, España) y Charleroi (Bélgica), 30 de octubre de 2020. Minoryx Therapeutics, una empresa biotecnológica en fase clínica II...
Friday, October 30, 2020

[4Fe-4S] cluster trafficking mediated by Arabidopsis mitochondrial ISCA and NFU proteins

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Tamanna Azam, Jonathan Przybyla-Toscano, Florence Vignols, Jérémy Couturier, Nicolas Rouhier, and Michael K. Johnson, J. Biol. Chem. jbc.RA1...
Thursday, October 29, 2020

An Overview of the Ferroptosis Hallmarks in Friedreich’s Ataxia

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Turchi, R.; Faraonio, R.; Lettieri-Barbato, D.; Aquilano, K. Biomolecules 2020, 10, 1489. doi:10.3390/biom10111489   Even though ferroptosis...
Monday, October 26, 2020

Gene Therapy Company AavantiBio Launches With $107 Million Series A Financing From Perceptive Advisors, Bain Capital Life Sciences, RA Capital Management and Sarepta Therapeutics

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CAMBRIDGE, Mass., Oct. 22, 2020 (GLOBE NEWSWIRE).   A premier syndicate of life sciences investors including Perceptive Advisors, Bain Capit...
Saturday, October 24, 2020

The French Association of Ataxia in Friedreich renews its 25,000 euro grant to validate the therapeutic potential of calcitriol for treating this rare malaltia

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IRBLleida, Friday, October 23, 2020. The French Association of Ataxia of Friedreich has renewed the aid of 25,000 euros to the Oxidative str...