Sunday, February 21, 2021

Frataxins Emerge as New Players of the Intracellular Antioxidant Machinery

›
Uceda, A.B.; Donoso, J.; Frau, J.; Vilanova, B.; Adrover, M.; Antioxidants 2021, 10, 315. doi:10.3390/antiox10020315  Consequently, our work...
Saturday, February 20, 2021

Energy deficit-independent stress response in the Frataxin-depleted heart: evidence that Integrated Stress Response can predominate over mTORC1 activation

›
Cesar Vasquez, Monika Patel, Aishwarya Sivaramakrishnan, Carmen Bekeova, Lauren Anderson-Pullinger, Nadan Wang, Hsin-Yao Tang, Erin L Seifer...
Friday, February 19, 2021

Friedreich’s Ataxia and Auditory Processing Disorder

›
Teive, H.A., Iliadou, V.M. & Manto, M.; Cerebellum (2021). doi:10.1007/s12311-021-01238-7 The link between auditory deprivation (in this...

Auditory Phenotypic Variability in Friedreich’s Ataxia Patients

›
Koohi, N., Thomas-Black, G., Giunti, P., Doris-Eva Bamiou.; Cerebellum (2021). doi:10.1007/s12311-021-01236-9 To our knowledge, this is the ...
Thursday, February 18, 2021

Hereditary Ataxia: A Focus on Heme Metabolism and Fe-S Cluster Biogenesis

›
Chiabrando D, Bertino F, Tolosano E.; Int J Mol Sci. 2020 May 26;21(11):3760. doi: 10.3390/ijms21113760. Mutations in genes involved in heme...
Sunday, February 14, 2021

Prognostic value of longitudinal strain and ejection fraction in Friedreich ataxia

›
L. Legrand, C. Heuze, A. Diallo, M.L. Monin, C. Ewenczyk, E. Vicaut, G. Montalescot, R. Isnard, A. Durr, F. Pousset. International Journal o...
Friday, February 12, 2021

Data Readout from Potentially Pivotal Phase 2/3 INAD Trial Expected 1H ‘01; Phase 2 ALS and Pivotal Phase 2/3 Friedreich’s Ataxia Trial Readouts Expected by Year-End

›
LOS ALTOS, Calif., Feb. 11, 2021 (GLOBE NEWSWIRE)​. RT001 Clinical Program Highlights: Friedreich’s Ataxia (FA) – Enrollment was completed i...

Future Prospects of Gene Therapy for Friedreich’s Ataxia

›
Ocana-Santero, G.; Díaz-Nido, J.; Herranz-Martín, S.; Int. J. Mol. Sci. 2021, 22, 1815. doi:10.3390/ijms22041815  Friedreich’s ataxia is an ...
Monday, February 8, 2021

Sheffield university team awarded £1.6m for drug research​​​​​​​ on motor neurone disease

›
Sheffield Telegraph; It will support their partnership with Aclipse Therapeutics to advance the translational development of M102 - a drug c...
Sunday, February 7, 2021

Gauging Gait Disorders with a Method Inspired by Motor Control Theories: A Pilot Study in Friedreich’s Ataxia

›
Gouelle, A.; Norman, S.; Sharot, B.; Salabarria, S.; Subramony, S.; Corti, M. Gauging; Sensors 2021, 21, 1144. doi:10.3390/s21041144   Organ...