Tuesday, April 28, 2026

Multimodal MRI and Machine Learning Uncovers Distinct Progression Patterns in Friedreich Ataxia

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Multimodal MRI and Machine Learning Uncovers Distinct Progression Patterns in Friedreich Ataxia. Susmita Saha, Nellie Georgiou-Karistianis,...
Monday, April 27, 2026

The TRKB Agonist 7,8-dihydroxyflavone Alleviates DNA Damage and Apoptosis in a Neuronal Cell Model of Friedreich’s Ataxia

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Galán-Cruz, J., Vicente-Acosta, A., Loría, F. et al. The TRKB Agonist 7,8-dihydroxyflavone Alleviates DNA Damage and Apoptosis in a Neuronal...

Novel Precision Gene Therapy for Friedreich’s Ataxia with Dr. Gabriel Brooks Solid Biosciences

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Apr 23, 2026 .  Solid Biosciences  Dr. Gabriel Brooks is Chief Medical Officer at Solid Biosciences, a precision molecular genetic medicines...

Nomlabofusp Treatment Produces Frataxin Levels That Correlate Across Peripheral Tissues: Preclinical and Clinical Support for Surrogate Tissue Sampling

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De Toni F, Hamdani M, Patadia C, Shankar G. Nomlabofusp Treatment Produces Frataxin Levels That Correlate Across Peripheral Tissues: Preclin...
Wednesday, April 22, 2026

Targeting exercise, energy, or both in Friedreich's ataxia

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Schulz J, Reetz K., Targeting exercise, energy, or both in Friedreich's ataxia,  The Lancet Neurology, 25, 435-437, doi:10.1016/S1474-44...

Safety and efficacy of individualised exercise and NAD+ precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial

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Lin K, Bucha A, McSweeney K et al. Safety and efficacy of individualised exercise and NAD+ precursor supplementation in patients with Friedr...
Wednesday, April 15, 2026

From Genetic Mutation to Therapy in Friedreich Ataxia: Molecular Mechanisms, Therapeutic Advances, and Translational Challenges

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Osaki, Y.; Haque, U. S.; Yokota, T. From Genetic Mutation to Therapy in Friedreich Ataxia: Molecular Mechanisms, Therapeutic Advances, an...
Sunday, April 12, 2026

Longitudinal analysis shows GAA1 length and baseline clinical status as robust predictors of progression in Friedreich ataxia

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Manrique L, Martínez-Dubarbie F, Pelayo-Negro AL, Benitez-Calle N, Sanchez-Pelaez MV, Cota-Gonzalez D, Loza R, Martinez-Díaz R, Irure-Ventur...
Friday, April 10, 2026

Hypomagnetic Fields Influence the Developmental Duration, Fecundity and Temperature Stress Resistance of Drosophila melanogaster via Frataxin-Associated Traits

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Kang H, Wan G, Zhang J, Pan W. Hypomagnetic Fields Influence the Developmental Duration, Fecundity and Temperature Stress Resistance of Dros...

Arctigenin derivative (ARC-18) improved mitochondrial dysfunction and ameliorated frataxin deficiency symptoms via PGC-1α signaling

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Gong Q, Han X, Liu T, Xiong B, Zhang B, Xie Y, Wan H, Ali T, Yang X, Li S. Arctigenin derivative (ARC-18) improved mitochondrial dysfunction...