Tuesday, July 7, 2026

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

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Sarwinska D, Buchholz M, Iskandar A, Grobe-Einsler M, Klockgether T, Faber J, Michalowsky B. Key Interventions in Friedreich's Ataxia an...
Friday, June 26, 2026

Nrf2 modulates cytosolic and mitochondrial calcium signal

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Alessandra Preziuso, Artyom Y. Baev, Fozila R. Rustamova, Sharadha Dayalan Naidu, Lauren Millichap, Plamena R. Angelova, Vincenzo Lariccia, ...
Thursday, June 25, 2026

LEXEO THERAPEUTICS ANNOUNCES REGULATORY UPDATE AND REGISTRATIONAL TRIAL DESIGN FOR LX2006 GENE THERAPY IN FRIEDREICH ATAXIA

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NEW YORK, June 15, 2026 (GLOBE NEWSWIRE) -- Lexeo Therapeutics, today announced that the Company has finalized the SUNRISE-FA 2 pivotal tria...

Drugging the ferroptotic landscape of Friedreich’s Ataxia: Current paradigms and future directions

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Cravin G, Cozza G. Drugging the ferroptotic landscape of Friedreich’s Ataxia: Current paradigms and future directions. Ferroptosis Oxid Stre...

Transitional Life Events in Friedreich Ataxia: Differential Age at Onset Perspectives

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Iskandar, A., Buchholz, M., Sarwinska, D. et al. Transitional Life Events in Friedreich Ataxia: Differential Age at Onset Perspectives. Cere...
Wednesday, June 24, 2026

AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich Ataxia: A Nonrandomized Clinical Trial

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Crystal RG, Weinsaft JW, Kaminsky SM, et al. AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich Ataxia: A Nonrandomized Clinical...
Tuesday, June 23, 2026

Polyphenols in mtDNA Repair, Mitochondrial Biogenesis, and Mitophagy: An Integrative Review

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Victoria-Montesinos, D., Barcina-Pérez, P., García-Muñoz, A.M. (2026). Polyphenols in mtDNA Repair, Mitochondrial Biogenesis, and Mitophagy:...

Genetic modifiers of Friedreich's ataxia pathophysiology in Drosophila melanogaster - A systematic review and meta-analysis

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Ravi Kant Yadav, Vishnu Swarup, Anami Ahuja, Dipesh Talukdar, Divyani Garg, Muraleedhar Aski, Achal Kumar Srivastava, Prachi Yadav, Genetic ...

Frataxin deficiency drives cardiac dysfunction and transcriptional dysregulation in Friedreich ataxia iPSC model

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Lees, J.G., Zhang, H., Jiao, L. et al. Frataxin deficiency drives cardiac dysfunction and transcriptional dysregulation in Friedreich ataxia...

Dysregulation of sphingolipid-metabolizing enzymes in Friedreich’s ataxia: In vitro and in vivo insights into therapeutic targeting

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Ramchunder Z, Kalef-Ezra E, Suleman S ..., Dysregulation of sphingolipid-metabolizing enzymes in Friedreich’s ataxia: In vitro and in vivo i...