Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPAR{gamma} pathway as a therapeutic target

Hum Mol Genet. 2009 Apr 17. [Epub ahead of print]
Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPAR{gamma} pathway as a therapeutic target in Friedreich's ataxia.
Coppola G, Marmolino D, Lu D, Wang Q, Cnop M, Rai M, Acquaviva F, Cocozza S, Pandolfo M, Geschwind DH.
Program in Neurogenetics, Department of Neurology David Geffen School of Medicine, University of California at Los Angeles, CA 90095.

OPEN ACCESS:

http://hmg.oxfordjournals.org/cgi/content/full/18/13/2452

http://hmg.oxfordjournals.org/cgi/reprint/18/13/2452.pdf