Friedreich Ataxia and close related scientific news. Topics related to rare diseases.
Thursday, March 24, 2022
Cerebellar Pathology in an Inducible Mouse Model of Friedreich Ataxia
Mercado-Ayón E, Warren N, Halawani S, Rodden LN, Ngaba L, Dong YN, Chang JC, Fonck C, Mavilio F, Lynch DR and Lin H (2022). Front. Neurosci. 16:819569. doi: 10.3389/fnins.2022.819569
Taken together, our findings show that frataxin knockdown leads to cerebellar degeneration in the FRDAkd mouse model, suggesting that frataxin helps maintain cerebellar structure and function.