A wearable motion capture suit and machine learning predict disease progression in Friedreich’s ataxia

Balasundaram Kadirvelu, Constantinos Gavriel, Sathiji Nageshwaran, Jackson Ping Kei Chan, Suran Nethisinghe, Stavros Athanasopoulos, Valeria Ricotti, Thomas Voit, Paola Giunti, Richard Festenstein & A. Aldo Faisal; Nat Med (2023). doi:10.1038/s41591-022-02159-6

Our work demonstrates how data-derived wearable biomarkers can track personal disease trajectories and indicates the potential of such biomarkers for substantially reducing the duration or size of clinical trials testing disease-modifying therapies and for enabling behavioral transcriptomics.

A wearable motion capture suit and machine learning predict disease progression in Friedreich’s ataxia