Health-Related Quality of Life in Patients with Friedreich Ataxia Using Mobility Assistive Technologies: Limited Fit of the EQ-5D-3L Mobility Dimension

Health-Related Quality of Life in Patients with Friedreich Ataxia Using Mobility Assistive Technologies: Limited Fit of the EQ-5D-3L Mobility Dimension. Maresa Buchholz, Michelle Pfaff, Audrey Iskandar, Kathrin Reetz, Jörg B. Schulz, Marcus Grobe-Einsler, Thomas Klockgether, Bernhard Michalowsky, EFACTS Study Group, Neurology and Therapy, Print ISSN: 2193-8253, Elektronische ISSN: 2193-6536, DOI: 10.1007/s40120-024-00694-7 

There are concerns about using HRQoL measures, such as the EQ-5D, in mobility-impaired individuals who had difficulties finding appropriate response options for mobility-related items. Our findings demonstrated limitations of the EQ-5D-3L mobility item in patients with FA using MAT, detecting a noticeable amount of non-responses in the mobility item in wheelchair users and a tendency to the mid-response level “some problems” in individuals using walking aids.

Health-Related Quality of Life in Patients with Friedreich Ataxia Using Mobility Assistive Technologies: Limited Fit of the EQ-5D-3L Mobility Dimension