Abnormal Brain Circuits May Prevent Movement Disorder

ScienceDaily (Aug. 4, 2009)
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Standaert says that although dystonia is a relatively rare disorder, the study has implications for other neurological illnesses, such as Parkinson's, Alzheimer's, and Huntington's diseases; ataxia and muscular dystrophies; and even forms of migraine.
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Source: The Journal of Neuroscience, August 5, 2009, 29(31):9740-9747; doi:10.1523/JNEUROSCI.2300-09.2009

Cerebellothalamocortical Connectivity Regulates Penetrance in Dystonia

Miklos Argyelan,^{1 *} Maren Carbon,^{1,2,3 *} Martin Niethammer,^1,2,3 Aziz M. Ulu,¹ Henning U. Voss,⁴ Susan B. Bressman,⁵ Vijay Dhawan,^1,2,3 and David Eidelberg^1,2,3

¹Center for Neurosciences, The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, New York 11030, Departments of ²Neurology and ³Medicine, North Shore University Hospital and New York University School of Medicine, Manhasset, New York 11030, ⁴Department of Radiology, Weill Cornell Medical College, New York, New York 10065, and ⁵Mirken Department of Neurology, Beth Israel Medical Center, New York, New York 10003