Targeting Friedreich Ataxia: A Sustainable Path to Safer and Smarter Therapeutics Through Integrated Docking and Toxicology

H. B. Attel, R. P, A. K, B. S, Shivandappa and S. Manokaran, "Targeting Friedreich Ataxia: A Sustainable Path to Safer and Smarter Therapeutics Through Integrated Docking and Toxicology," 2024 8th International Conference on Computational System and Information Technology for Sustainable Solutions (CSITSS), Bengaluru, India, 2024, pp. 1-4, doi: 10.1109/CSITSS64042.2024.10816941. 

 Our study aims to develop novel therapeutic candidates by leveraging computational protein-ligand docking through the Galaxy EU platform, targeting frataxin deficiencies. High-throughput docking and toxicology studies have identified several promising compounds with potential therapeutic efficacy, offering hope for more effective and sustainable treatments for FA.