Low-dose idebenone treatment in Friedreich's ataxia with and without cardiac hypertrophy.

http://www.ncbi.nlm.nih.gov/pubmed/19363628?dopt=AbstractPlus&holding=f1000,f1000m,isrctn

J Neurol. 2009 Apr 12. [Epub ahead of print]

Low-dose idebenone treatment in Friedreich's ataxia with and without cardiac hypertrophy.

Rinaldi C, Tucci T, Maione S, Giunta A, De Michele G, Filla A.
Department of Neurological Sciences, University of "Federico II", Via Pansini, 5, 80131, Naples, Italy, rinaldi.ca@gmail.com.

Creating Ideal Neural Cells For Clinical Use

http://www.sciencedaily.com/releases/2009/04/090413141303.htm

Creating Ideal Neural Cells For Clinical Use
ScienceDaily (Apr. 13, 2009) — Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation.

Human ES Cells Progress Slowly In Myelin's Direction

http://www.sciencedaily.com/releases/2009/04/090409103342.htm
Human ES Cells Progress Slowly In Myelin's Direction
ScienceDaily (Apr. 9, 2009) — Scientists from the University of Wisconsin report in the journal Development the successful generation from human embryonic stem cells of a type of cell that can make myelin, a finding that opens up new possibilities for both basic and clinical research.

Risk of Stroke and Thrombus Formation From Delay Incontinence of a PLAATO-Device in Friedreich Ataxia

1: Clin Cardiol. 2009 Apr 7. [Epub ahead of print]Risk of Stroke and Thrombus Formation From Delay Incontinence of a PLAATO-Device in Friedreich Ataxia.Stöllberger C, Finsterer J, Avanzini M, Mölzer G, Weidinger F.Second Medical Department, Krankenanstalt Rudofstiftung.We present the case of a 76-year-old female with suspected Friedreich ataxia, in whom leakage and thrombosis of a percutaneously implanted left atrial appendage occluder (PLAATO) was observed 2 years after implantation. Because of late developing leakages and thrombi, regular transesophageal echocardiographic examinations should be carried out in patients with occluded left atrial appendagaes. In view of these complications and the potential important hemodynamic role of the left atrial appendage, the benefit of its occlusion is questionable, and the indications of PLAATO should be strongly reconsidered. Copyright (c) 2009 Wiley Periodicals, Inc.PMID: 19353681 [PubMed - as supplied by publisher] Source: http://www.ncbi.nlm.nih.gov/pubmed/19353681

Team Regrows Neurons Controlling Movement in Rats

http://news.yahoo.com/s/hsn/20090406/hl_hsn/teamregrowsneuronscontrollingmovementinrats;_ylt=AsWK6hIycwjUHGBmTJZ0CTy3j7AB

Team Regrows Neurons Controlling Movement in Rats
By Jennifer ThomasHealthDay Reporter by Jennifer Thomashealthday Reporter – Mon Apr 6, 7:04 pm ET
MONDAY, April 6 (HealthDay News) --

Diagnosis and treatment of Friedreich ataxia: a European perspective.

http://www.ncbi.nlm.nih.gov/pubmed/19347027?dopt=Abstract

Nat Rev Neurol. 2009 Apr;5(4):222-34.
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Diagnosis and treatment of Friedreich ataxia: a European perspective.

Schulz JB, Boesch S, Bürk K, Dürr A, Giunti P, Mariotti C, Pousset F, Schöls L, Vankan P, Pandolfo M.

Department of Neurology, University Hospital, RWTH Aachen, Aachen, Germany.

VIRxSYS Publishes New Study On RNA Therapy

http://www.medicalnewstoday.com/articles/145267.php

Article Date: 07 Apr 2009 - 0:00 PDT

VIRxSYS Publishes New Study On RNA Therapy

Axons Necessary For Voluntary Movement Regenerated

http://www.sciencedaily.com/releases/2009/04/090406192229.htm

Axons Necessary For Voluntary Movement Regenerated



Adapted from materials provided by University of California - San Diego, via EurekAlert!, a service of AAAS

All-you-can-eat: autophagy in neurodegeneration and neuroprotection

http://www.molecularneurodegeneration.com/content/4/1/16

full text: http://www.molecularneurodegeneration.com/content/pdf/1750-1326-4-16.pdf

All-you-can-eat: autophagy in neurodegeneration and neuroprotection
Philipp A Jaeger and Tony Wyss-Coray
Molecular Neurodegeneration 2009, 4:16doi:10.1186/1750-1326-4-16

Published: 6 April 2009

Novel insights into iron metabolism by integrating deletome and transcr iptome analysis in an iron deficiency model of the yeast Saccharomyces cerevis

http://www.biomedcentral.com/1471-2164/10/130/abstract

Full text: http://www.biomedcentral.com/content/pdf/1471-2164-10-130.pdf

Novel insights into iron metabolism by integrating deletome and transcr iptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae
William J. Jo1,9, Jeung Hyoun Kim1,9, Eric Oh1,9, Daniel Jaramillo2, Patricia Holman1, Alex V. Loguinov1, Adam P. Arkin3,4, Corey Nislow5,6,8, Guri Giaever5, 7, 8 and Chris D. Vulpe 1,10 1 Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California 94720 2 Stanford Genome Technology Center, Stanford University, Palo Alto, California 94304 3 Department of Bioengineering, University of California, Berkeley, California 94720 4 Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 5 University of Toronto, Department of Molecular Genetics, Toronto, Ontario M5S3E1, Canada 6 University of Toronto, Banting and Best Department of Medical Research, Toronto, Ontario M5S3E1, Canada 7University of Toronto, Department of Pharmaceutical Sciences, Toronto, Ontario M5S3E1, Canada 8 University of Toronto, Donnelley Centre for Cellular and Biomolecular Research, Toronto, Ontario M5S3E1, Canada 9 These authors contributed equally on this paper 10 Corresponding author: 119 Morgan Hall, University of California, Berkeley, California 94720, Phone: (510) 642-
1834, Fax: (510) 642-0535 Email addresses: WJJ williamjo@berkeley.edu; JHK jhkim19@berkeley.edu; EO eric_oh@berkeley.edu; DJ nddano@gmail.com; PH ttyholman@yahoo.com; AVL Avl53@aol.com; APA aparkin@lbl.gov; CN corey.nislow@utoronto.ca; GG guri.giaever@utoronto.ca; CDV vulpe@berkeley.edu