The neuroprotective and neurorescue effects of carbamylated erythropoietin Fc fusion protein (CEPO-Fc) in a rat model of Parkinson’s disease

The neuroprotective and neurorescue effects of carbamylated erythropoietin Fc fusion protein (CEPO-Fc) in a rat model of Parkinson’s disease; Judith Thomas Tayra, Masahiro Kameda, Takao Yasuhara, Takashi Agari, Tomohito Kadota, Feifei Wang, Yoichiro Kikuchi, Hanbai Liang, Aiko Shinko, Takaaki Wakamori, Brigitta Vcelar,Brain Research, Volume 1502, 28 March 2013, Pages 55–70. http://dx.doi.org/10.1016/j.brainres.2013.01.042

Keywords: Carbamylated erythropoietin, Dopamine, Neuroprotection, Neurorescue, Parkinson’s disease

Brain-Computer Interfaces Make New Tasks As Simple As Waving A Hand

Brain-Computer Interfaces Make New Tasks As Simple As Waving A Hand. University of Washington. (2013, June 14). "Brain-Computer Interfaces Make New Tasks As Simple As Waving A Hand." Medical News Today

This technology could improve communication and daily life for a person who is paralyzed or has lost the ability to speak from a stroke or neurodegenerative disease.

Friedreich’s and other hereditary ataxias in Greece: an 18-year perspective

Friedreich’s and other hereditary ataxias in Greece: an 18-year perspective Georgios Koutsis, Athina Kladi, Georgia Karadima, Henry Houlden, Nicholas W. Wood, Kyproula Christodoulou, Marios Panas. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)

Genetic delineation of early onset cerebellar ataxia phenotypes in India through next generation sequencing

Genetic delineation of early onset cerebellar ataxia phenotypes in India through next generation sequencing Mohammed Faruq, Ankita Narang, Renu Kumari, Achal Kumar Sriavstava, Debasis Dash, Mitali Mukerji. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)

Addressing Mitochondrial Function in a mouse model of Friedreich’s Ataxia (FRDA)

Addressing Mitochondrial Function in a mouse model of Friedreich’s Ataxia (FRDA) Rosella Abeti, Michael Parkinson, Chiranjeevi Sandi, Mark Pook, Andrey AY Abramov and Paola Giunti. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)

Autosomal recessive cerebellar ataxias : cinical and genetic study of 188 patients

Autosomal recessive cerebellar ataxias : cinical and genetic study of 188 patients Lamia Ali-Pacha, W Hamza S Nouioua, C Lagier-Tourenne, Traki Benhassine, S Assami, Michel Koenig, Meriem Tazir. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)

Retrospectively and prospectively Study of 188 cases belonging to 117 families coming from different regions of Algeria, between 2001 à 2012, patients suspected of Autosomal recessive cerebellar ataxias. The molecular diagnosis could be established in 67% of Autosomal recessive cerebellar ataxias patients (126 patients belonging to 75 families): 52 patients (32 families) were affected with Friedreich ataxia, it was the most frequent entity, as found in the majority of studies, followed by AOA2 and AVED.

Burden of Friedreich’s Ataxia to the patients and healthcare systems in the United States and Canada

Burden of Friedreich’s Ataxia to the patients and healthcare systems in the United States and Canada. Polek Barbara, Andrews William T, Roach MT, Ehling Manfred, Salek Sam; Front. Pharmacol., 22 May 2013 | doi: 10.3389/fphar.2013.00066

Conclusion: The variety of healthcare measures addressing the broad range of symptoms of FRDA, and the increasing use of paid home care as disease progresses made total US healthcare costs of FRDA exceed the costs of US adults with two and more chronic conditions. Therefore, measures delaying disease progression will allow patients to maintain their independence longer and may reduce costs to the healthcare system. Novel measures to address dysarthria and to ensure access to them should be further investigated. The higher than average private funding ratio in Canada was due to the relatively high cost of the pharmacological treatment of FRDA.


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Therapeutic strategies in Friedreich's Ataxia

Therapeutic strategies in Friedreich's Ataxia. Timothy E. Richardson, Heather N. Kelly, Amanda E. Yu, James W. Simpkins.; Brain Research, Volume 1514, 13 June 2013, Pages 91-97; http://dx.doi.org/10.1016/j.brainres.2013.04.005

Keywords: Friedreich's Ataxia, Therapeutic Strategies, Frataxin, 17β-estradiol, Methylene blue

The balancing act of DNA repeat expansions

The balancing act of DNA repeat expansions. Jane C Kim, Sergei M Mirkin; Current Opinion in Genetics & Development, Available online 29 May 2013, http://dx.doi.org/10.1016/j.gde.2013.04.009,

Keywords: repeat expansions, replication, repair, recombination, transcription.

Friedreich's ataxia associated with subaortic membrane : A rare case.

Friedreich's ataxia associated with subaortic membrane : A rare case. Doğan A, Aksoy H, Simşek H., Herz. 2013 May 29.

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