A Digital Measure of Eye Movements During Reading Sensitively Captures Oculomotor and Speech Dysfunction, Early Changes, and Disease Progression in Ataxias

Oubre, B., Yang, F., Luddy, A.C., Manohar, R., Soja, N.N., Stephen, C.D., Schmahmann, J.D., Kulkarni, D., White, L., Patel, S. and Gupta, A.S. (2025), A Digital Measure of Eye Movements During Reading Sensitively Captures Oculomotor and Speech Dysfunction, Early Changes, and Disease Progression in Ataxias. Ann Neurol. doi:10.1002/ana.78039 

Digital measures of eye movements are a promising approach for sensitively measuring ataxia in clinical trials (including early-stage disease) and may have utility in other neurodegenerative diseases affecting speech or ocular control. 

A Digital Measure of Eye Movements During Reading Sensitively Captures Oculomotor and Speech Dysfunction, Early Changes, and Disease Progression in Ataxias