6:22AM Thu February 11, 2010
Wednesday, February 10, 2010
Frataxin, a molecule of mystery: trading stability for function in its iron-binding site
Biochem. J. (2010) 426 (e1–e3) (Printed in Great Britain)
Darius J. R. Lane* and Des R. Richardson†1
*Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Melbourne, Victoria, 3800, Australia, and †Department of Pathology and Bosch Institute, Iron Metabolism and Chelation Program, Blackburn Building, University of Sydney, Sydney, New South Wales, 2006, Australia
Key words: frataxin, Friedreich's ataxia (FRDA), iron–sulfur cluster, Isu protein, mitochondrion, yeast frataxin (Yfh1).
Darius J. R. Lane* and Des R. Richardson†1
*Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Melbourne, Victoria, 3800, Australia, and †Department of Pathology and Bosch Institute, Iron Metabolism and Chelation Program, Blackburn Building, University of Sydney, Sydney, New South Wales, 2006, Australia
Key words: frataxin, Friedreich's ataxia (FRDA), iron–sulfur cluster, Isu protein, mitochondrion, yeast frataxin (Yfh1).
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