Resveratrol Highlights

http://www.lmcfood.dk/fileadmin/lmc_files/food/Kristensen-5_Resveratrol-Cell-2006.pdf

Lagouge et al., Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1a,
Cell (2006), doi:10.1016/j.cell.2006.11.013

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1a

Marie Lagouge,8,1 Carmen Argmann,8,1 Zachary Gerhart-Hines,2 Hamid Meziane,3 Carles Lerin,2
Frederic Daussin,4 Nadia Messadeq,3 Jill Milne,5 Philip Lambert,5 Peter Elliott,5 Bernard Geny,4 Markku Laakso,6
Pere Puigserver,2 and Johan Auwerx1,3,7,* 1 Institut de Ge´ ne´ tique et de Biologie Mole´ culaire et Cellulaire, CNRS / INSERM / ULP, 67404 Illkirch, France
2Department of Cell Biology, John Hopkins University School of Medicine, Baltimore, MD 21205, USA
3 Institut Clinique de la Souris, BP10142, 67404, Illkirch, France
4Department of Respiratory, Cardiocirculatory and Exercise Physiology, Hoˆ pitaux Universitaires, 67000 Strasbourg, France
5 Sirtris Pharmaceutical, Cambridge, MA 02139, USA
6Department of Medicine, University of Kuopio, 70211 Kuopio, Finland
7IGBMC-ICS, 67404 Illkirch, France
8These authors contributed equally to this work.

*Contact: auwerx@igbmc.u-strasbg.fr

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http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=85386&Ausgabe=230907&ProduktNr=224154&filename=85386.pdf

Neurosignals 2005;14:61–70
DOI: 10.1159/000085386
Received: December 6, 2004
Accepted after revision: March 1, 2005

Unique Properties of Polyphenol Stilbenes in the Brain: More than Direct Antioxidant Actions; Gene/Protein Regulatory Activity

Sylvain Doré
Johns Hopkins University, School of Medicine, Baltimore, Md. , USA

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http://www.ncbi.nlm.nih.gov/pubmed/18629638?dopt=Abstract

Neurochem Res. 2008 Dec;33(12):2444-71. Epub 2008 Jul 16.

Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity.

Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E.Section of Biochemistry and Molecular Biology, Department of Chemistry, Faculty of Medicine, University of Catania, Viale Andrea Doria 6, 95100, Catania, Italy. calabres@unict.it


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http://www3.interscience.wiley.com/journal/121682622/abstract?CRETRY=1&SRETRY=0

Histone Deacetylase Inhibition Activity and Molecular Docking of (E )-Resveratrol: Its Therapeutic Potential in Spinal Muscular Atrophy

Didem Dayangaç-Erden 1,*, Gamze Bora 1 , Peruze Ayhan 2 , Çetin Kocaefe 1 , Sevim Dalkara 3 , Kemal Yelekçi 4 , Ayhan S. Demir 2 and Hayat Erdem-Yurter 1
1 Department of Medical Biology, Faculty of Medicine, Hacettepe University, Ankara, Turkey 2 Department of Chemistry, Middle East Technical University, Ankara, Turkey 3 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey 4 Department of Statistics and Computer Sciences, Faculty of Arts and Science, Kadir Has University, Istanbul, Turkey
Correspondence to *Dr Didem Dayangaç-Erden, didayan@hacettepe.edu.tr
Copyright Journal compilation © 2009 Blackwell Munksgaard
KEYWORDS
(E )-resveratrol • molecular docking • SMN2 • spinal muscular atrophy

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http://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPDF/resveratrol.pdf